Purpose To evaluate the diagnostic accuracy of a novel non-contrast brain MRI method based on semiautomatic lesion detection using T2w FLAIR subtraction image, the statistical detection of change (SDC) algorithm (T2w + SDC), and quantitative susceptibility mapping (QSM). This method identifies new lesions and discriminates between enhancing and nonenhancing lesions in multiple sclerosis (MS). ...

BACKGROUND The risk factors of predicting the need for postoperative decompressive craniectomy due to intracranial hypertension after primary craniotomy remain unclear. This study aimed to investigate the value of intraoperative intracranial pressure (ICP) monitoring in predicting re-operation using salvage decompressive craniectomy (SDC). METHODS From January 2008 to October 2014, we retrosp...

A new class of iterative time parallel methods for initial value ordinary differential equations are developed. Methods based on a parallel variation of spectral deferred corrections (SDC) are compared and contrasted with the parareal method. It is shown that there is a strong similarity between the serial step in the parareal algorithm and the correction step in the SDC method. This observatio...

In this work, the challenges associated with formation of single and bilayer coatings based on Ce0.8Sm0.2O1.9 (SDC) CuO modified BaCe0.5Zr0.3Y0.1Yb0.1O3?? (BCZYYbO-CuO) solid state electrolytes porous non-conducting NiO-SDC anode substrates by method electrophoretic deposition (EPD) are considered. Various approaches that had been selected after analysis literature data in order to carry out EP...

The formation and plasticity of synaptic connections rely on regulatory interactions between pre- and postsynaptic cells. We show that the Drosophila heparan sulfate proteoglycans (HSPGs) Syndecan (Sdc) and Dallylike (Dlp) are synaptic proteins necessary to control distinct aspects of synaptic biology. Sdc promotes the growth of presynaptic terminals, whereas Dlp regulates active zone form and ...

BACKGROUND Recent quality initiatives require that the routine annual therapeutic drug-monitoring (TDM) parameters for the high-risk medication digoxin include a measure of renal function and a serum potassium level but not a serum digoxin concentration (SDC) measurement. Several studies have shown that the majority of the SDCs obtained in hospital settings provide little clinically actionable ...

The presentation of secreted axon guidance factors plays a major role in shaping central nervous system (CNS) connectivity. Recent work suggests that heparan sulfate (HS) regulates guidance factor activity; however, the in vivo axon guidance roles of its carrier proteins (heparan sulfate proteoglycans, or HSPGs) are largely unknown. Here we demonstrate through genetic analysis in vivo that the ...

The relationship among diet, human health, and disease is an area of growing interest in biomarker research. Previous studies suggest that the consumption of cranberries (Vaccinium macrocarpon) could beneficially influence urinary and digestive health. The present study sought to determine if daily consumption of sweetened dried cranberries (SDC) changes the urinary proteome and fecal microbiom...

BACKGROUND The survival rates and prognostic factors for salivary duct carcinoma (SDC) are not clear. METHODS Survival estimates and prognostic factors were evaluated for 228 patients with SDC identified from the Surveillance, Epidemiology, and End Results (SEER) database. RESULTS Median overall survival (OS) duration for patients with SDC was 79 months and 5-year disease-specific survival ...