The risk of death during intensive remission induction therapy (‘treatment-related mortality’; TRM) for adults with acute myeloid leukemia (AML) has substantially decreased over the last two decades, likely largely because of improved supportive care measures. Still, AML patients remain prone to morbidity during the prolonged duration of diseaseand treatment-related cytopenia, especially with r...

Point-of-Interest (POI) recommendation has become an important means to help people discover attractive and interesting places, especially when users travel out of town. However, extreme sparsity of user-POI matrix creates a severe challenge. To cope with this challenge, we propose a unified probabilistic generative model, Topic-Region Model (TRM), to simultaneously discover the semantic, tempo...

Tissue-resident memory CD8 T cells (TRM) provide preemptive immunity against infections that begin in peripheral tissues by guarding the site of initial pathogen exposure. Their role in immunity to respiratory virus infection is particularly important because severe damage to the alveoli can be avoided when local populations of TRM cells reduce viral burdens and dampen the responses of effector...

The 1998 Computer Generated Forces (CGF) Conference included a paper [1] which proposed a Technical Reference Model (TRM) for interoperability between U.S. Command, Control, Communication, Computers, Intelligence, Reconnaissance, and Surveillance systems (C4ISR) and Computer Generated Force simulations (Sim). This TRM characterized the “type of information that is necessary to pass between C4IS...

Motivated by understanding the phase structure of d > 1 strings we investigate the c = 1 matrix model with g(trM(t)) interaction which is the simplest approximation of the model expected to describe the critical phenomena of the large-N reduced model of odd-dimensional matrix field theory. We find three distinct phases: (i) an ordinary c = 1 gravity phase, (ii) a branched polymer phase and (iii...

Both total nucleated cell (TNC) dose and human leukocyte antigen (HLA)-match affect the outcome of cord blood (CB) transplantation. However, how to prioritize these characteristics in unit selection is not established. Therefore, we analyzed the outcomes of 1061 patients who received single-unit myeloablative CB transplantation for leukemia or myelodysplasia. TNC dose and HLA-match each affecte...

BACKGROUND In this study, we established a hypothetical tumor-lodds-metastasis (TLM) and tumor-ratio-metastasis (TRM) staging system. Moreover, we compared them with the 7(th) edition of American Joint Committee on Cancer tumor-nodes-metastasis (AJCC TNM) staging system in gastric cancer patients after D2 resection. METHODS A total of 1000 gastric carcinoma patients receiving treatment in our...

Psoriasis is a common and chronic inflammatory skin disease in which T cells play a key role. Effective treatment heals the skin without scarring, but typically psoriasis recurs in previously affected areas. A pathogenic memory within the skin has been proposed, but the nature of such site-specific disease memory is unknown. Tissue-resident memory T (TRM) cells have been ascribed a role in immu...

[1] Pan et al. [2002] experimentally investigated the validity of the Shaw paleointensity method [Shaw, 1974; Kono, 1978; Rolph and Shaw, 1985] using laboratoryinduced thermal remanent magnetization (TRM) to simulate natural remanent magnetization (NRM). They prepared fully demagnetized Cretaceous basalt samples by exposing them to a 150-mT alternating field (AF), and then heating them in an ov...