Idiotypes and antiidiotypes are thought to be important immune regulators and have provided clues for the origin and pathogenicity of autoantibodies. Many lupus and Sjögren's syndrome patients, as well as most neonatal lupus infants with congenital heart block or dermatitis, have antibodies to the ribonucleoprotein Ro/SSA, which is one of a group of RNA-protein autoantigens commonly found in hu...

Extract: The conventional wisdom about why species age and live as long as they do is based in part on the modern version of the very old and now discredited "rate of living" (ROL) theory of aging. According to the old ROL theory, aging is caused by the loss of some vital substance such as water or hormones - the more rapid the vital substance is used up the shorter the lifespan. The modern and...

Lettuce is an important edible crop which possesses various medicinal properties. In this study Lactuca sativa L. (cv Grand Rapids) was transformed by Agrobacterium-mediated transformation with rol C gene. Transgene integration and expression was confirmed through PCR and semiquantitative RT-PCR. The transformed extracts were evaluated for their in vitro antioxidant and in vivo analgesic, anti-...

Obesity negatively affects multiple metabolic pathways, but little is known about the impact of obesity on vitamin A (VA)[retinol (ROL)], a nutrient that regulates expression of genes in numerous pathways essential for human development and health. We demonstrate that obese mice, generated from a high fat diet (HFD) or by genetic mutations (i.e., ob/ob; db/db), have greatly reduced ROL levels i...

Resumen Actual men te se acep ta que la ad ven ti cia tie ne: un im por tan te rol fi sio ló gi co al de ter mi nar el ni vel de nu tri ción, oxi ge na ción, re pa ra ción ar te rial, re gu la ción de la va so mo tri ci dad, con trol de la pos car ga ven tri cu lar, con trol de la fun ción ar te rial, et cé te ra, a la vez que tie ne una im por tan te par ti ci pa ción en pro ce sos pa to ló gi...

rol insects and ectoparasites viz., Hemiptera, particularly aphids, poglycaemia, hypoproteinemia, The present article was conducted to review the various pharmaceutical, environmental exposure and through feed on poultry Heavy metals possess high density and toxicity towards living beings. -8713 IJPRBS

ROL is a deductive object base language being developed at the University of Regina. It integrates important features of deductive and object-oriented databases. It supports object identity, complex objects, class hierarchy, multiple inheritance with overriding and blocking, and schema. It also supports structured values such as functor objects and sets, treats them as rst class citizens, and p...

Özet. Anlamsal web, web içeriklerinin diğer yazılımlar tarafından anlaşılabilir, yorumlanabilir, kullanılabilir olmasını ve bilginin paylaşılmasını amaçlamaktadır. Anlamsal web’de bilginin güvenliği erişim denetimi ile sağlanmaktadır. OBAC(Ontology Based Access Control – Ontoloji Tabanlı Erişim Denetimi) verinin anlamsal tanımının olduğu ontolojilere erişim denetiminin sağlanmasında kullanılan ...

Pichia pastoris has been recognized as an effective host for recombinant protein production. In this work, we combine metabolomics and instationary 13C metabolic flux analysis (INST 13C-MFA) using GC-MS and LC-MS/MS to evaluate the potential impact of the production of a Rhizopus oryzae lipase (Rol) on P. pastoris central carbon metabolism. Higher oxygen uptake and CO2 production rates and slig...

Rhizopus oryzae lipase (ROL) has a propeptide at its N-terminus that functions as an intramolecular chaperone and facilitates the folding of mature ROL (mROL). In this study, we successfully generated a functionally distinct imprinted mROL (mROLimp) through protein folding memory using a mutated propeptide. The mutated propeptide left its structural memory on mROL and produced mROLimp that exhi...