نتایج جستجو برای: ژن tcda
تعداد نتایج: 16022 فیلتر نتایج به سال:
An origami-based Tightly Coupled Dipole Array (TCDA) is proposed for small satellite applications. The array formed by a two-layered structure using rigid and flexible substrates to enable accordion-like folding. TCDA operates across 0.4-2.4 GHz with VSWR < 3 at broadside 0.6-2.4 when scanning down 45∘ in the E-, D-, H-plane. 8 × prototype was fabricated Kapton Polyimide FR4 tested verify bandw...
The toxins TcdA and TcdB produced by the human pathogen Clostridium difficile gain entrance to host epithelial cells by recognizing cell-surface carbohydrate ligands. Inhibiting the attachment of these toxins to host cells has been proposed to be a viable therapy to treat C. difficile infections. Glycan array screening previously revealed that the Le(A)-LacNAc pentasaccharide binds strongly to ...
Working memory (WM) is limited in capacity, but it is controversial whether these capacity limitations are domain-general or are generated independently within separate modality-specific memory systems. These alternative accounts were tested in bimodal visual/tactile WM tasks. In Experiment 1, participants memorized the locations of simultaneously presented task-relevant visual and tactile stim...
In Colombia, the epidemiology and circulating genotypes of Clostridium difficile have not yet been described. Therefore, we molecularly characterized clinical isolates of C.difficile from patients with suspicion of C.difficile infection (CDI) in three tertiary care hospitals. C.difficile was isolated from stool samples by culture, the presence of A/B toxins were detected by enzyme immunoassay, ...
Due to the huge potential of application in communications, electronic jamming, and radar fields, circularly polarized (CP) array antennas with wide axial ratio (AR) scanning performance at frequency bandwidth have received great attention. A wideband CP planar antenna built by new, tightly coupled dipole (CP-TCDA) elements, which achieved promising results terms both AR angle range all planes,...
Host anti-toxin immune responses play important roles in Clostridium difficile disease and outcome. The relationship between host immune and inflammatory responses during severe C. difficile infection (CDI) and the risk of mortality has yet to be defined. We aimed to investigate the host systemic IgG anti-toxin immune responses, the in vitro cytotoxicity of the infecting C. difficile ribotyped ...
Toxin A variant strains (toxin A-negative, toxin B-positive strains) of Clostridium difficile have been reported to be responsible for diarrhea or pseudomembranous colitis in humans. These strains lack parts of the repeating sequences of the toxin A gene (tcdA) and are toxin A negative by commercial enzyme immunoassays (EIA). Here, we report the prevalence of the toxin A variant strains in 334 ...
Toxin gene analysis of a variant strain of Clostridium difficile that causes human clinical disease.
A toxin variant strain of Clostridium difficile was isolated from two patients with C. difficile-associated disease (CDAD), one of whom died from extensive pseudomembranous colitis. This strain, identified by restriction endonuclease analysis (REA) as type CF2, was not detected by an immunoassay for C. difficile toxin A. Culture supernatants of CF2 failed to elicit significant enterotoxic activ...
UNLABELLED Clostridium difficile is a leading cause of antibiotic-associated diarrhea, a significant animal pathogen, and a worldwide public health burden. Most disease-causing strains secrete two exotoxins, TcdA and TcdB, which are considered to be the primary virulence factors. Understanding the role that these toxins play in disease is essential for the rational design of urgently needed new...
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