نتایج جستجو برای: 0002 and 004

تعداد نتایج: 16829266  

Journal: :Blood 1996
H J Deeg G Socié G Schoch M Henry-Amar R P Witherspoon A Devergie K M Sullivan E Gluckman R Storb

Risk factors for the development of a new (secondary) malignancy after marrow transplantation are still incompletely defined. In the present study, we analyzed results in 700 patients with severe aplastic anemia treated with allogeneic marrow transplantation at the Fred Hutchinson Cancer Research Center in Seattle, WA, or at the Hôpital St Louis in Paris, France. Twenty-three patients developed...

Journal: :Pediatric Rheumatology 2013

Journal: :International journal of pharmaceutics 2017
Andrew Bristol Steven Hubert Felix Hofmann Hans Baer

SYN-004 (ribaxamase) delayed release drug product is a multi-particulate, hard capsule for oral delivery of a recombinant β-lactamase enzyme designed to degrade β-lactam antibiotics administered intravenously, and thus prevent colon dysbiosis. Here we describe the development of the SYN-004 enteric coated pellet formulation, which has been tested in multiple clinical trials. Since the SYN-004 d...

Journal: :Bioresource technology 2010
Qingyi Xu Zengshe Liu Mitsutoshi Nakajima Sosaku Ichikawa Nobutaka Nakamura Poritosh Roy Hiroshi Okadome Takeo Shiina

This paper characterizes the physico-chemical properties of the soybean oil-based polymeric surfactant, Palozengs R-004 (hereafter referred to as R-004). The surface activity of R-004 is comparable to the reported activities of biosurfactants produced by microorganisms and higher than some of the conventional synthetic surfactants. The surface tension of Milli-Q water was reduced to a minimum v...

کادمیوم از جمله فلزاتی می‌باشد که به­طور وسیع در محیط پراکنده است. منبع اصلی این فلز ترکیبات صنعتی و کودهای فسفاته می‌باشد. این فلز توسط گیاهان جذب شده و در بافت­هایی مانند کبد و کلیه تجمع یافته و باعث بروز کم­خونی، افزایش فشار خون، تخریب بافت بیضه و عوارض استخوانی می‌شود. با توجه به عوارض متعدد وجود کادمیوم، لازم است در مناطق مختلف مطالعه‌ای در ارتباط با میزان آلودگی شیر تولیدی گاوها به این فل...

2016
Lucia D’Ambruoso Kathleen Kahn Ryan G. Wagner Rhian Twine Barry Spies Maria van der Merwe F. Xavier Gómez-Olivé Stephen Tollman Peter Byass

[This corrects the article DOI: 10.1186/s41256-016-0002-y.].

2008
Ariadne GUTIÉRREZ Rafael GÁMEZ Maikel VALLE Eddy GOICOCHEA Dayisell CURVECO Nilda MENDOZA

D-004, a lipid extract from royal palm (Roystonea regia) fruits, has shown to inhibit prostate 5-α-reductase in vitro, and to prevent prostate hyperplasia (PH) induced with T, not with DHT, in rodents, but its potential estrogenic or antiestrogenic effects had not been studied yet. This study investigated whether D-004 produces estrogenic or antiestrogenic effects, as assessed in the uterotroph...

Journal: :European Journal of Hospital Pharmacy 2013

Journal: :The Journal of pharmacology and experimental therapeutics 1998
I Ishii N Yokoyama M Yanagimachi N Ashikawa M Hata S Murakami Y Asami N Morisaki Y Saito S Ohmori M Kitada

A new inhibitor of acyl CoA:cholesterol acyltransferase (ACAT), HL-004 [N-(2, 6-diisopropylphenyl)tetradecylthioacetamide], suppressed the synthesis of cholesterol [14C]oleate at 10(-9) approximately 10(-7) M in a concentration-dependent manner in both THP-1 cell-derived macrophages and foam cells prepared from aortic intima of rabbits fed a high cholesterol diet. Incorporation of [3H]cholester...

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