Free radicals produce detrimental effects on target molecules, like increased lipid, protein and DNA peroxidation, which can be inhibited or delayed by antioxidant substances. D-003 is a mixture of high molecular weight sugarcane wax acids that has shown to inhibit lipid peroxidation (LP) in animal models and healthy volunteers. Grape seed extracts (GSE), rich in flavonoids, have demonstrated p...

The highly restricted distribution of human folate receptor-alpha (FRα) in normal tissues and its high expression in some tumors, along with its putative role in tumor cell transformation, make this antigen a suitable target for antigen-specific, monoclonal antibodybased immunotherapy for oncology indications. We have developed a therapeutic humanized monoclonal antibody with high affinity for ...

Twenty-six cases of Blastoschizomyces capitatus infection were diagnosed in 25 patients at 7 tertiary care hematology units in Spain over a 10-year period. Most patients (92%) had acute leukemia and developed infection during a period of severe and prolonged neutropenia. Two patients had esophagitis, and the rest had invasive infection. Fungemia (20 cases) was a common finding, with frequent vi...

Our aim is to determine--in 30 healthy full-term infants and their mothers--circulating levels of neurotrophin-3 (NT-3) (important for antenatal and postnatal brain development and implicated in the immune response) and FLT3 tyrosine kinase receptor (FLT3) (controlling hematopoiesis and found in the nervous tissue), in the fetal and neonatal life. NT-3 levels, in contrast to FLT3 ones, increase...

Non-typhoidal Salmonella (NTS) is a common pathogen causing foodborne infections, bacteraemia, and extra-intestinal focal infections (EFIs) in humans. The study compares the clinical characteristics of elderly patients with NTS bacteraemia with those of young adults. Of 272 adults with NTS bacteraemia identified in this study, 162 (59·6%) were aged ⩾55 years. EFIs were observed in 36% of the 16...

To achieve strong, successful and commercial aqua-biotechnological microalgae applications, screening, isolation, molecular identification, physiological characterizations are needed. In the current study, a native cyanobacteria strain Arthrospira platensis NIOF17/003 was isolated from surface water of El-Khadra Lake, saline-alkaline lake located in Wadi El-Natrun, Egypt. The cyanobacterium phy...

Original papers 488 Study of the effect of time availability on the consultation Leone Ridsdale, Maria Carruthers, Richard Morris and Jane Ridsdale 492 Mathematical relationship between waiting times and appointment interval for doctor and patients Ian Hill-Smith 495 Factors affecting the decision to consult with dyspepsia: comparison of consulters and non-consulters Susan Lydeard and Roger Jon...