Neurotrophin-3 (NT-3) is one of the most potent stimulators for survival of auditory sensory neurons. Viral transfer of neurotrophins into auditory neurons may offer a route to provide a permanent supply of the growth factor and guarantee their long-term survival. Herpes simplex virus type 1 (HSV-1)-based vectors have demonstrated their effectiveness to transfer genes into peripheral sensory ne...

In a recent study we demonstrated that reasoning with categorical syllogisms engages two dissociable mechanisms. Reasoning involving concrete sentences engaged a left hemisphere linguistic system while formally identical arguments, involving abstract sentences, recruited a parietal spatial network. The involvement of a parietal visuo–spatial system in abstract syllogism reasoning raised the que...

Least squares support vector machines (LS-SVM) is an SVM version which involves equality instead of inequality constraints and works with a least squares cost function. In this way, the solution follows from a linear Karush–Kuhn–Tucker system instead of a quadratic programming problem. However, sparseness is lost in the LS-SVM case and the estimation of the support values is only optimal in the...

In this study we present a novel automated strategy for predicting infarct evolution, based on MR diffusion and perfusion images acquired in the acute stage of stroke. The validity of this methodology was tested on novel patient data including data acquired from an independent stroke clinic. Regions-of-interest (ROIs) defining the initial diffusion lesion and tissue with abnormal hemodynamic fu...

Objectives: To examine the characteristics of evoked and induced gamma band oscillatory responses occurring during P300 development in an auditory oddball paradigm. Methods: A time-frequency analysis method was applied to an auditory oddball paradigm in 7 healthy subjects. This method combines a multiresolution wavelet algorithm for signal extraction and the Gabor transform to represent the tem...

E4ective annotation and content-based search for videos in a digital library require a preprocessing step of detecting, locating and classifying scene transitions, i.e., temporal video segmentation. This paper proposes a novel approach— spatial–temporal joint probability image (ST-JPI) analysis for temporal video segmentation. A joint probability image (JPI) is derived from the joint probabilit...

The nonstationary variation in the noise performance of the cross-correlation-based strain estimator due to frequency-dependent attenuation and lateral and elevational signal decorrelation have been addressed theoretically in recent papers using the strain-filter approach. In this paper, we present the experimental verification and corroboration of the nonstationary effects on the strain estima...

Numerous physiological conditions as well as behavioral conditions have been shown to influence central nervous system vascular structure. Many of the methods used to investigate these structural alterations take advantage of the visibility of viscous substances (e.g. India ink in gelatin) perfused into the vasculature. The high viscosity of the solution, however, can cause incomplete vessel pe...

Objective: Bronchioloalveolar lung carcinoma (BAC) is characterized by bronchial and lymphatic dissemination explaining multifocal and bilateral spreading. Bilateral BAC is usually considered as a contraindication to surgery. Regarding poor efficacy of symptomatic and oncological treatments, we hypothesized that surgery might play a role to palliate hypoxemia associated with serious intrapulmon...

We study the consequences of omnivory on the dynamic behaviour of a three species food web under chemostat conditions. The food web consists of a prey consuming a nutrient, a predator consuming a prey and an omnivore which preys on the predator and the prey. For each trophic level an ordinary differential equation describes the biomass density in the reactor. The hyperbolic functional response ...