The seasons associated with laboratory isolation of respiratory syncytial virus (RSV) (for 1981-2004) and RSV-related emergency department admissions (for 1990-2004) ended 3.1 and 2.5 weeks earlier, respectively, per 1 degrees C increase in annual central England temperature (P=.002 and .043, respectively). Climate change may be shortening the RSV season.

BACKGROUND Targeted alpha therapy has been postulated to have great potential for the treatment of small clusters of tumour cells as well as small metastases. (213)Bismuth, an α-emitter with a half-life of 46 min, has shown to be effective in preclinical as well as in clinical applications. In this study, we evaluated whether (213)Bi-[DOTA(0), Tyr(3)]-octreotate ((213)Bi-DOTATATE), a (213)Bi-la...

We previously investigated the potential of targeted radiotherapy using a bismuth-213 ((213)Bi)-labeled anti-CD45 antibody to replace total body irradiation as conditioning for hematopoietic cell transplantation in a canine model. Although this approach allowed sustained marrow engraftment, limited availability, high cost, and short half-life of (213)Bi induced us to investigate an alternative ...

Abstract Agitation is experienced by over 90% of individuals with Alzheimer’s disease (AD) which increases morbidity and mortality contribute to caregiver burden. There are no FDA-approved treatments for severe agitation in people advanced dementia. Behavioral interventions first-line management strategies but not effective the most severely agitated patients. Off-label use psychotropic medicat...

Given permutations σ ∈ Sk and π ∈ Sn with k < n, the pattern matching problem is to decide whether π matches σ as an orderisomorphic subsequence. We give a linear-time algorithm in case both π and σ avoid the two size-3 permutations 213 and 231. For the special case where only σ avoids 213 and 231, we present aO(max(kn, n log(log(n))) time algorithm. We extend our research to bivincular pattern...

OBJECTIVE To determine absorption coefficients for sodium chloride solution (saline) and balanced salt solution at the 193- and 213-nm laser wavelengths. METHODS Absorption coefficients were obtained for each of the component species found in balanced salt solution. This was achieved by measuring laser pulse transmission through solutions of varying concentration. The experiments were repeate...

INTRODUCTION ............................................................. 198 CELLULAR LIPIDS ......................................................... 198 Extraction .................................................................. 198 Subcellular Distribution .................................................... 198 Cytoplasmic (plasma) membrane .......................................... 198...