Within the ovarian cancer microenvironment, there are several mechanisms that suppress the actions of antitumor immune effectors. Delineating the complex immune microenvironment is an important goal toward developing effective immune-based therapies. A dominant pathway of immune suppression in ovarian cancer involves tumor-associated and dendritic cell (DC)-associated B7-H1. The interaction of ...

Abstract. Let σ δ k denote the Cesàro means of order δ > −1 of the spherical harmonic expansions on the unit sphere Sd−1, and let Ej ( f, H1) denote the best approximation of f in the Hardy space H1(Sd−1) by spherical polynomials of degree at most j . It is known that λ := (d −2)/2 is the critical index for the summability of the Cesàro means on H1(Sd−1). The main result of this paper states th...

Cancer stem-like cells (CSCs) are a rare tumorigenic population with the ability to self-renew in numerous cancer types. Their existence is considered a pivotal contributor to tumor recurrence. B7-H1 is a ligand of inhibitory inducible co-stimulator (ICOS) that is broadly expressed on various human cancers. ICOS acts as a ligand of programmed death-1 (PD-1) on T cells, induces the immune escape...

Human endothelial cells (ECs) provide costimulatory signals sufficient to activate resting memory T cells to produce IL-2 and IFN-gamma, at least in part through CD58-CD2 interactions. Recently, the B7-like molecule, B7-H1 (PD-L1), was described and shown to regulate T cell activation; however, there are conflicting reports on whether it stimulates or inhibits T cell cytokine synthesis. B7-H1 i...

Article history: Received 18 February 2014 Accepted 18 February 2014 Available online 17 March 2014 We provide a correction to the proof of the main result in Crupi and Tentori (2013). © 2014 Elsevier B.V. All rights reserved. Michael Schippers (University of Oldenburg) pointed out to us in personal correspondence an error in the proof of the main result in Crupi and Tentori [1]. The flaw spott...

In this paper we establish mapping properties of bilinear Coifman-Meyer multipliers acting on the product spaces H1(Rn)×bmo(Rn) and Lp(Rn)×bmo(Rn), with 1<p<∞. As application these results, obtain some related Kato-Ponce-type inequalities involving endpoint space bmo(Rn), also study pointwise a function in bmo(Rn) functions H1(Rn), h1(Rn) Lp(Rn),

where Ω is a bounded domain in Rn (1 ≤ n ≤ 3), f is a nonlinear map.We use the homogeneous Sobolev space H1 0 (Ω)(≡ H1 0 ) for the solution of (1). Also some appropriate assumptions are imposed on the map f . In order to treat the problem as the finite procedure, we use a finite element subspace Sh of H1 0 with mesh size h. Denoting the inner product on L2(Ω) by (·, ·), we define the H1 0 -proj...

The present paper is a note on the relative tensor degree of finite groups. This notion generalizes the tensor degree, introduced recently in literature, and allows us to adapt the concept of relative commutativity degree through the notion of nonabelian tensor square. We show two inequalities, which correlate the relative tensor degree with the relative commutativity degree of finite groups. 1...