In the present paper we consider Cauchy-type problem associated to space-time fractional differential equation \begin{document}$ \partial_t u+\partial_t^{\beta}(-\Delta)^{1-\beta}u-\Delta u = g(t, x), \quad t>0, \ x\in \mathbb R^n $\end{document} with $ \beta\in (0, 1) $, where derivative \partial_t^{\beta} is in Caputo sense and (-\Delta)^{1-\beta} Laplace operator of order 1-\beta $. We pr...

Background: Normal tissue toxicity continues to remain as a major challenge for radiation oncologists for delivering the total dose to the tumour cells in cancer patients. Cellular, molecular and plasma based early biomarkers to predict the overreactions and non-overreactions of normal tissue toxicity before the initiation of radiotherapy can be valuable for personalised treatment. The aim of t...

background and objectives : the rapid emergence and dissemination of carbapenemase-producing klebsiella pneumoniae strains and other members of the enterobacteriaceae poses a considerable threat to the care of hospitalized patients and to public health. the aim of this study was to determine the frequency of metallo-β-lactamases (mbl) and vim-1 gene in multidrug-resistant strains of k. pneumoni...

background: pseudomonas aeruginosa is the causing agent of many hospital infections and metallo-beta-lactamases (mbl) are being reported with increasing frequency. the aim of this study was to determine the frequency of metallo-&beta-lactamases; (mbl) and vim-1 gene in multidrug-resistant strains of p. aeruginosa isolates and to compare the methods of phenotypic and molecular detection. materia...

Background: Transforming growth factor-β1 (TGF-β1) has been found to play a crucial role in early central nervous system development. Several studies have illustrated decreased TGF-β1 levels in sera and brains of autistic children. Two point mutations in the TGF-β1 signal peptide at 869T/C and 915G/C have been reported to influence TGF-β1 expression. The aim of the pres...

Introduction: In order to study the alterations of beta 1 and 2 integrins mRNA level in rat lumbar spinal cord following the induction of chronic pain and its effect on the development of tolerance to morphine analgesia, we examined the level of expression of these genes in the presence of chronic pain, which is an inhibitor of morphine tolerance. We used induction of chronic pain alone and ...