BACKGROUND Effects of vitamin D deficiency in pregnancy have been associated with some adverse pregnancy outcomes. The 25-hydroxyvitamin D3-1α-hydroxylase (CYP27B1) is integral to the vitamin D metabolic pathway. The enzyme catalyzes localized conversion of pro-hormone 25-hydroxyvitamin D3 to active 1,25-dihydroxyvitamin D3. Our aim was to investigate the expression of CYP27B1 at the fetal-mate...

Recruitment maneuvers (RM), consisting of sustained inflations at high airway pressures, have been advocated as an adjunct to mechanical ventilation in acute respiratory distress syndrome (ARDS). We studied the effect of baseline ventilatory strategy and RM on end-expiratory lung volume (EELV) and oxygenation in 18 dogs, using three models of acute lung injury (ALI; n = 6 in each group): saline...

To verify whether there is a loss of radioactive microspheres (RM) from regions undergoing myocardial infarction, we injected 7-10 fan RM into the left atrium in 75 dogs before left circumflex (LC) coronary artery occlusion and measured the myocardial RM content when the dogs were killed 696 hours later. The preocclusion RM content per gram in the occluded LC bed was not significantly different...

We investigate the role of banks in the ownership structure of non-…nancial …rms. Distinguishing between banks and other institutional investors as shareholders, we examine the relationship between …nancial institution ownership and the performance of the …rms in which they hold equity. We control explicitly for the capital structure decision of the …rms and the ownership decision of …nancial i...

This study was designed to investigate the dynamics of the paternal genome demethylation in pronuclear-stage bovine zygotes produced either by in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) using freeze-thawed (FT) as well as freeze-dried (FD) bull sperm stored at +4 or -196 C for one year. Zygotes were fixed and immunostained using anti-5-methyl-cytosin at 8, 10, 14 an...

Introduction. In acute respiratory distress syndrome (ARDS) the recruitment maneuver (RM) is used to reexpand atelectatic areas of the lungs aiming to improve arterial oxygenation. The goal of our paper was to evaluate the response to RM, as assessed by measurements of extravascular lung water index (EVLWI) in ARDS patients. Materials and Methods. Seventeen adult ARDS patients were enrolled int...