Objective: We administered intraoperative pectoral nerve block after tissue resection was over and assessed its analgesic efficacy with conventional post-operative intravenous opioids in patients undergoing modified radical mastectomy. Methods: Sixty mastectomy surgery were enrolled this prospective, randomized, doubleblinded study. After general anesthesia surgical both groups, Group P receive...

Abstract Background Syphilis in pregnancy is common Africa with prevalence as high 10%. In areas ( > 5%), WHO recommends universal syphilis screening and benzathine penicillin G treatment at the first antenatal clinic (ANC) visit. Implementation barriers include global stock outs supply chain issues. Our goal was to document rates factors associated lack of among pregnant women Zambia. M...

Modulation of central 5-HT receptor sensitivity is implicated in the therapeutic response to electroconvulsive shock (ECS). Altered 5-HT receptor expression may play a role in this process. We have measured the mRNAs encoding 5-HT1A, 5-HT2A, 5-HT2C and 5-HT7 receptors, and the 5-HT transporter, in rat brain after single ECS, repeated ECS, and 3 weeks after repeated ECS. Hippocampal 5-HT1A recep...

This study used structural magnetic resonance imaging (MRI) to investigate associations between brain structure and saccadic eye movements. Seventeen healthy subjects underwent structural MRI and infra-red oculographic assessment of a reflexive saccade task. Volumes of prefrontal, premotor, and occipitoparietal cortex, caudate, thalamus, and cerebellar vermis were used as predictors in multiple...

Dietary porcine brain phospholipids are much more efficient than soybean phospholipids for ensuring a normal (optimal obtained with lab chow diet) level of docosahexaenoic acid (DHA) in tissues and brain subcellular fractions (brain myelin and nerve endings). Two weeks before mating, rats were divided into two groups (one group was subdivided into subgroups, fed with varying amounts of porcine ...

Human embryonic kidney 293 (HEK-293) cells stably transfected with the human serotonin (5-HT) or dopamine transporter (hSERT, hDAT), or the rat GABA transporter GAT-1 were incubated with saturating concentrations of transporter substrates (hSERT: [H]5-HT, [H]N-methyl-phenyl-pyridinium (MPP1); hDAT: [H]dopamine, [H]MPP; rGAT: [H]GABA). Uptake velocities decreased signi®cantly over time for [H]5-...

Slices (400 mm) containing the area postrema were prepared from three Japanese house musk shrews. Data reported are from 16 representative units. Units fell into one of three separate groups with spontaneous ®ring rates of 36±41/s, 16± 18/sec. and 6±8/sec., possibly re ̄ecting different set points of an endogenous pacemaker. Most neurons did not respond to ionophoresis of GABA or ACh. In those t...

Children’s attention is easily diverted from a current activity to a new event in the environment. This was indexed in school-age children by diminished performance speed and accuracy in a visual discrimination task caused by taskirrelevant novel sounds. Event-related brain potentials (ERPs) elicited by these distracting sounds showed a prominent positive deflection that was generated by brain ...

Our objectives were to determine the feasibility of recording reliable multifocal visual evoked magnetic fields (mfVEFs), to investigate the maximum stimulus eccentricity for which the mfVEF responses can be obtained, and to study how this changes with checksize (spatial frequency tuning). Using a checksize of 30 0, we recorded 8-channel pattern-onset mfVEFs three times to obtain responses from...