BACKGROUND Wolfram Syndrome (WS) is an autosomal recessive neurodegenerative disorder characterized by Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness identified by the acronym "DIDMOAD". The WS gene, WFS1, encodes a transmembrane protein called Wolframin, which recent evidence suggests may serve as a novel endoplasmic reticulum calcium channel in pancreatic β-cells and neuro...

INTRODUCTION Contact dermatitis is a relatively common dermatosis reported among several population groups from all around the globe. However, the data from Kuwait is unavailable. Patch tests are essential for the diagnosis of contact sensitization. AIM To determine a relative frequency and pattern of sensitizers to different allergens in patients of suspected contact dermatitis in Kuwait and...

Abstract In the paper “On rigid germs of finite morphisms smooth surfaces” ( Sb. Math. , 211:10 (2020), 1354–1381), we defined a map from set $\mathcal R$?> equivalence classes branched in curves having $ADE$?> singularity types onto $\mathcal{B}el$?> rational Belyi pairs $f\colon\mathbb P^1\,{\to}\,\mathbb P^1$?> considered up to action $\mat...

We introduce a class of $\gamma$-negatively dependent random samples. prove that this includes, apart from Monte Carlo samples, in particular Latin hypercube samples and padded by Carlo. For $N$-point sample dimension $d$ we provide probabilistic upper bounds for its star discrepancy with explicitly stated dependence on $N$, $d$, $\gamma$. These generalize the [Heinrich et al., Acta Arith. 96 (...

Rev Esp Cardiol. 2005;58(12):1381-4 1381 We are all well aware of the important advances made in the realm of cardiology in recent years, but, undoubtedly, they have had a special impact in the realm of congenital heart disease. Since 1938, when Robert Gross performed the first ligature of a patent ductus arteriosus; 1944, when William Blalock, pressured by Helen Taussig, created the first syst...

Family firms are the most ubiquitous form of business organization in any world economy. Business Review, Journal Strategy, and Management three leading academic journals exclusively dedicated to this type firms. Since inception first 1988, these outlets published 1381 articles dealing with family business. This study offers a comprehensive bibliometric overview contributions, thereby providing...