نتایج جستجو برای: 15 gene
تعداد نتایج: 1586212 فیلتر نتایج به سال:
extant limpet. In addition, bivalves also acquired a novel structure, adducter muscle to close the separated shell plate. Because the two novel structures, the separated shell plate and the adducter muscle appear early embryonic stage, their evolution should be understood as a modification of early development. To understand the evolution of bivalve bodyplan, we have traced the cleavage pattern...
Recently, 5-hydroxymethylcytosine patterning across the tumor genome was considered as a hallmark of cancer development and progression. However, locus-specific difference of hydroxymethylation between colorectal cancer and normal tissue is unknown. In this study, we performed a newly developed method, HMST-seq, to profile 726 aberrant methylated loci and 689 aberrant hydroxymethylated loci syn...
PURPOSE The newly discovered human kallikrein 15 gene KLK15 has been shown in preliminary analysis to be associated with more aggressive types of prostate cancer. We quantitatively measured and compared gene expression of KLK15 in malignant and benign prostate tissues. MATERIALS AND METHODS Matched prostate tissue samples from the cancerous and noncancerous parts of the same prostates were ob...
Denys-Drash syndrome (DDS) and Frasier syndrome (FS) are caused by mutations of the WT1 gene. These disorders are characterized by renal disease, abnormality of male sex differentiation, and Wilms' tumor and gonadoblastoma. There have been few reports on gonadal function in a large series of patients with mutations of the WT1 gene. Here, we evaluated the relation between gonadal function and th...
Functional gene description: The sensory systems reponsible for maintenance of equilibrium and balance are ontained within the vestibular portion of the inner ear. The toconial complex, an extracellular structure containing igh-density particles called otoconia, renders the receptor ells of the sensory macular epithelium responsive to gravity. he major matrix protein (otoconin-90, OC90) account...
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