Hyaluronan (HA) and chondroitin sulfate clearance from lymph and blood is mediated by the hyaluronan receptor for endocytosis (HARE). The purification and molecular cloning (Zhou, B., Weigel, J. A., Saxena, A., and Weigel, P. H. (2002) Mol. Biol. Cell 13, 2853-2868) of this cell surface receptor were finally achieved after we developed monoclonal antibodies (mAbs) against HARE. There are actual...

508 PEDIAmIcs, March 1958 DR. LEVINE : The patient to be presented is an infant who had chronic diarrhea. Studies performed on this patient by Dr. Murray Davidson, Assistant Professor of Clinical Pediatrics, suggest that there are multiple factors involved in the production of the celiac syndrome. Dr. Davidson will discuss the patient’s illness and observations made. DR. MURRAY DAVIDSON: To man...

Note: G/C polymorphism at nucleotide -174 (promoter region) Breast cancer prognosis differs between populations. Despite its lower incidence in Blacks when compared to Caucasians, mortality among the former is higher. Genetic factors involved in the molecular pathways regulating tumor development have been adduced to explain these differences, and it has been suggested that the IL-6 gene is a s...