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تعداد نتایج: 2092843 فیلتر نتایج به سال:
Dysregulation of cholesterol homeostasis is associated with various metabolic diseases, including atherosclerosis and type 2 diabetes. The sterol response element binding protein (SREBP)-2 transcription factor induces the expression of genes involved in de novo cholesterol biosynthesis and low density lipoprotein (LDL) uptake, thus it plays a crucial role in maintaining cholesterol homeostasis....
185/333 genes and transcripts from the purple sea urchin, Strongylocentrotus purpuratus, predict high levels of amino acid diversity within the encoded proteins. Based on their expression patterns, 185/333 proteins appear to be involved in immune responses. In the present study, one- and two-dimensional Western blots show that 185/333 proteins exhibit high levels of molecular diversity within a...
Lung epithelial cell death is a prominent feature involved in the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Hyperoxia-induced ALI is an established animal model mimicking human ARDS. Small noncoding RNAs such as microRNAs (miRNAs) have potent physiological and pathological functions involving multiple disease processes. Emerging interests focus on th...
چکیده: هدف: هدف از پژوهش حاضر مقایسه حافظه (کوتاه مدت، بلند مدت و بصری) در بیماران مبتلا به دیابت نوع 2 و افراد سالم می باشد. روش: روش پژوهش از نوع علی مقایسه ای است. جامعه آماری این تحقیق را کلیه بیماران مبتلا به دیابت نوع 2 ساکن شهرستان پارس آباد و روستاهای اطراف آن تشکیل می دهند. از بین این جامعه، 40 نفر از بیماران مراجعه کننده به پزشکان متخصصین داخلی و پزشکان خانواده که در شهرستان پارس آبا...
Increasing evidence has shown that microRNAs play critical roles in the initiation and progression of non-small cell lung cancer (NSCLC). miR-185 is deregulated in various cancers, whereas its functional mechanism in NSCLC is still unclear. Here, we confirmed that the expression of miR-185 was significantly down-regulated in NSCLC tissues and cell lines. miR-185 over-expression caused significa...
PURPOSE Brachytherapy plays a major role in the treatment of patients with carcinoma of the cervix. However, routine intracavitary brachytherapy may not be feasible or adequate to treat locally advanced disease. The purpose of this retrospective study (spanning a 20-year period) was to determine the outcome of interstitial low-dose-rate brachytherapy in the treatment of bulky or locally advance...
Melanoma is an aggressive malignancy that is increasingly common and exhibits a poor patient survival rate. Radiotherapy is the primary option for patients with melanoma, particularly those who are not candidates for surgery; however, the therapeutic effect is limited due to the relative radioresistance of melanoma to ionizing radiation (IR). It has been reported that microRNAs (miRNAs) serve a...
Samenvatting 185 Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 Samenvatting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 186
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