In isotropic solution, internuclear dipolar couplings average to zero as a result of rotational diffusion. By dissolving macromolecules in a dilute aqueous nematic discotic liquid-crystalline medium containing widely spaced magnetically oriented particles, a tunable degree of solute alignment with the magnetic field can be created while retaining the high resolution and sensitivity of the regul...

This study aimed to use an existing ligand (imidazole)-assisted 1H-nuclear magnetic resonance (1H-NMR) spectroscopy protocol determine sulfate content of seaweed sulfated saccharides. Twenty samples – spanning nine species and multiple geographic locations were analyzed. Extracts obtained by immersing freeze-dried seaweeds in boiling water, followed alginate precipitation. Remaining supernatant...

A new impurity was detected during high performance liquid chromatographic (HPLC) analysis of eslicarbazepine acetate active pharmaceutical ingredient. The structure of unknown impurity was postulated based on liquid chromatography mass spectrometry using electrospray ionization and ion trap analyzer (LC/ESI-IT/MS) analysis. Proposed structure of impurity was unambiguously confirmed by synthesi...

Nuclear magnetic resonance (NMR) spectroscopy was employed for the purpose of identifying samples of materials suspected of containing sodium fluoroacetate (Compound 1080). Acquisition of routine proton (1H) and carbon (13C) NMR spectra provided a straight-forward means for determining the presence of Compound 1080 in the samples and thus afforded a simple method for analysis and identification...

Methylation, 1H nuclear magnetic resonance, and bacteriophage degradation results indicate that the Escherichia coli serotype K30 capsular polysaccharide consists of leads to 2)-alpha-D-Manp-(1 leads to 3)-beta-D-Galp-(1 leads to chains carrying beta-D-GlcUAp-(1 leads to 3)-alpha-D-Galp-(1 leads to branches at position 3 of the mannoses.

The interaction specificity of salmon sperm DNA with 2-hydroxyethanethionlato(2,2',2''-terpyridine)platinum(II),PtTS has been studied. The results of 1H and 13C nuclear magnetic resonance, flow dichroism and circular dichroism studies are found to be consistent with an intercalation mode of binding as has been proposed earlier by lippard and coworkers.

The ylides Ph3E-C6H6N2O3 (7, E = P (a), As (b), Sb (c)) have been prepared through the reaction of Ph3E and 5bromo-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione (5-bromo-1,3-dimethylbarbituric acid) 6 in the presence of triethylamine. Their characterisation was performed by nuclear magnetic resonance (NMR), mass spectrometry (MS) and elemental analysis.

Rhodamine 6G-chromone-derived compounds RD1 - RD4 have been synthesized by condensation of rhodamine 6G hydrazide and substituted chromone aldehydes in ethanol using microwave-assisted reaction. The structures these derivatives were confirmed proton nuclear magnetic resonance (1H-NMR), carbon (13C-NMR), high-resolution mass spectra data (HRMS). Colorimetric photophysical studies show the select...

A catalyst-free synthetic strategy to chromene carbonitriles by Multi-Component Reaction of pyrazole aldehydes, 5,5-dimethylcyclohexane-1,3-dione and malononitrile with ethanol, at room temperature is reported. Screening solvents purification the compounds were also performed. The newly synthesized novel compound’s (4H-chromene-3-carbonitriles) structures authenticated spectral techniques viz. ...

Microwave-assisted reactions are an environmentally friendly approach for synthesizing organic compounds. In this study, oximation of acetylferrocene and acetophenone was conducted under both microwave irradiation conventional heating conditions. Acetylferrocene were subjected to the two conditions in various solvent mixtures, extent conversion determined by 1H nuclear magnetic resonance spectr...