BACKGROUND Redox cycling compounds have been reported to cause false positive inhibition of proteases in drug discovery studies. This kind of false positives can lead to unusually high hit rates in high-throughput screening campaigns and require further analysis to distinguish true from false positive hits. Such follow-up studies are both time and resource consuming. METHODS AND FINDINGS In t...

The stereochemical divergent synthesis of indolyl-pyrrolidines was accomplished using an imidazoline-aminophenol (IAP)-Ni(OAc)2 complex and a bis(imidazolidine)pyridine (PyBidine)-Cu(OTf)2 complex. The former catalyzed exo'-selective asymmetric [3 + 2] cyclization of iminoesters with indolyl nitroalkenes, and the latter catalyzed the reaction in an endo-selective manner. These catalysts are tol...

A single crystal of organic nonlinear optical material 3-aminophenol perchlorate (3-AMP) was successfully grown by the slow evaporation solution method. Single-crystal X-ray diffractrometer was utilized to measure unit cell parameters and to confirm lattice parameter. 3-aminophenol perchlorate belongs to monoclinic space group P21. The optical transparency window in the UV–vis-NIR region is fou...

CdO nanoparticles efficiently catalyzes the condensation of aromatic aldehydes with 2-aminophenol at room temperature to afford 2-aryl benzoxazole derivatives by grinding method. The reactions proceed under heterogeneous and mild conditions to provide 2-aryl benzoxazoles in excellent yields (87-97 %) with high purity under solvent free condition. The reaction requires short time (5-23 minutes) ...

The capillary electromigration method is an important analytical technique known for its simplicity, sensitivity, and selectivity. We have investigated electrophoretically mediated microanalysis (EMMA) in plug-plug and continuous formats for the determination of phenolic compounds. The azocoupling reactions of phenol, 3-aminophenol, and resorcinol with 4nitrophenyldiazonium fluoroborate were ca...

Two-dimensional x-ray correlation spectra (2DXCS) obtained by varying two delay periods in a time-resolved coherent all-x-ray four-wave-mixing measurement are simulated for the N 1s and O 1s transitions of aminophenol. The necessary valence and core-excited states are calculated using singly and doubly substituted Kohn-Sham determinants within the equivalent-core approximation. Sum-over-states ...

Maleic anhydride was reacted with p-aminophenol and p-toluidine in the presence of di-phosphorus pentoxide (P₂O₅) as a catalyst to produce two compounds: N-(4-hydroxy-phenyl)maleimide (I) and N-(4-methylphenyl)maleimide (II). The new azo compounds I(a-c) and II(a-c) were prepared by the reaction of I and II with three different aromatic amines, namely aniline, p-aminophenol and p-toluidine. The...

Abstract The introduction of a -NO 2 substituent in o -aminophenol would create an open-unit polymer suitable for different applications. We report the synthesis poly(5-nitro-2-aminophenol) by aniline-catalyzed oxidative polymerization. structure was intensively characterized spectroscopic techniques, elemental analysis, cyclic voltammetry, electrical conductivity and microscopic measurements s...