Exendin-4 is a long-acting potent agonist of the glucagon-like peptide 1 (GLP-1) receptor and may be useful in the treatment of type 2 diabetes and obesity. We examined the effects of an intravenous infusion of exendin-4 (0.05 pmol. kg(-1). min(-1)) compared with a control saline infusion in healthy volunteers. Exendin-4 reduced fasting plasma glucose levels and reduced the peak change of postp...

In this work, computational fluid dynamics simulations are carried out to assess the ability of control surfaces alleviate or suppress transonic buffet. Among available surfaces, upper trailing edge flaps were considered since they modify aerofoil pressure distribution and fix shock at an upstream position. Spoilers also studied as produce a similar effect by interfering with disturbance propag...

Swimming may stimulate appetite and food intake but empirical data are lacking. This study examined appetite, food intake, and plasma acylated ghrelin responses to swimming. Fourteen healthy males completed a swimming trial and a control trial in a random order. Sixty min after breakfast participants swam for 60 min and then rested for six hours. Participants rested throughout the control trial...

two series (a and b) of n- substituted heteroaromatic compounds related to clotrimazole were synthesized. imidazole ring of the clotrimazole was replaced by 2-methylimidazole in series a, and by 2-methyl-4-nitroimidazole in series b. o-cholortrityl moiety of clotrimazole was also replaced by trityl, mono or dimethoxy trityl. chemical structures of all the new compounds were confirmed by spec-tr...

background: 2, 4-dichlorophenoxy acetic acid (2, 4-d) is well known as inexpensive herbicides but it can give rise to undesirable pollution. the objective of this investigation was to describe a photo-chemical system for degradation of 2, 4-d. methods: a designed photolytic cell system was used in this study with a 150w or 400w uv lamp. a set of experiments was carried out at ph 1.5, 2.5, 3.5 a...