Highlights . Elevated levels of matrix metalloproteinases 2 and 9 are associated with the initiation severity CHF developed after breast cancer therapy anthracyclines, which may contribute to cardiac remodeling progression systolic dysfunction. Concentrations metalloproteinases-2 -9 in blood serum serve as predictors unfavorable course anthracycline-induced heart failure. Aim To assess role (MM...

A chondrosarcoma is a common tumor of the soft tissue and bone that has high propensity to metastasize distant organs. Nerve growth factor (NGF) capable promoting progression metastasis several different types tumors although effects NGF in are not confirmed. Here, we found levels matrix metalloproteinase-2 (MMP-2) correlated with stage patients chondrosarcoma. facilitated MMP-2-dependent cellu...

objective(s):n-myc downstream regulated gene 2 (ndrg2) is a candidate gene for tumor suppression. the expression of ndrg2 is down-regulated in several tumors including lung cancer. the aim of this study was to explore the effect of ndrg2 overexpression on invasion, migration, and enzymatic activity of matrix metalloproteinase-2 (mmp-2) and -9 (mmp-9) in human lung adenocarcinoma a549 cells.  ma...

Purpose Failed Back Surgery Syndrome (FBSS) occurs in 10–40% of patients treated surgically due to disk herniation (DH). There are several factors that can cause a predisposition FBSS, but the exact pathomechanism has not been elucidated. The aim this study was investigate Metalloproteinase-2 (MMP-2) and Tissue Inhibitor (TIMP-2) activities homogeneous group FBSS with epidural fibrosis comparis...