Military night vision goggles (NVGs) are image intensifiers normally used when the human operator's visual capabilities are unimpaired by oxygen deprivation. However, mountain search team members and aviators sometimes operate with NVG augmentation at altitudes where hypoxic visual decrement is documented. The objective of this research was to investigate the effects of mild hypoxia on monocula...

High Mountain Asia hosts the largest glacier concentration outside the polar regions. These glaciers are important contributors to streamflow in one of the most populated areas of the world. Past studies have used methods that can only provide regionally-averaged glacier mass balances to assess the High Mountain Asia glacier contribution to rivers and sea level rise. Here we compute the mass ba...

A micro-pulse lidar system (MPL) was used to measure the vertical and horizontal distribution of aerosols during the Aerosol Characterization Experiment 2 (ACE-2) in June and July of 1997. The MPL measurements were made at the Izaña observatory (IZO), a weather station located on a mountain ridge (28°18∞N, 16°30∞W, 2367 m asl ) near the center of the island of Tenerife, Canary Islands. The MPL ...

A focused search in very high (2500–3200 m asl) Alpine mountain tops France resulted the discovery of rare Alpine-endemic syrphid Platycheirus altomontis Merlin & Nielsen Nielsen, 2004, including its hitherto unknown female. description female is given and further complemented with behavioural observations this species special reference to hilltopping. Additional records are provided for ne...

Stem radial variations of Corsican Black pine (Pinus nigra Arnold subsp. laricio Maire) and Maritime pinaster Aiton) were monitored to quantify the impact two meteorologically contrasting consecutive years. On French island Corsica, in western Mediterranean basin, year 2017 was extremely dry, while 2018 exceptionally wet. We attached electric band dendrometers 36 pines along an east–west transe...

Biogeographic barriers for freshwater biota can be effective at various spatial scales. At the largest spatial scale, freshwater organisms can become genetically isolated by their high mountain ranges, vast deserts, and inability to cross oceans. Isolation by distance of aquatic plants is expected to be stronger across than alongside mountain ridges whereas the heterogeneity of habitats among p...

Arginine biosynthesis and nitric oxide (NO) production are important for cancer homeostasis. Degradation of arginine may be used to inhibit liver tumors with low argininosuccinate synthetase (ASS) expression. In this report, we investigated an alternative therapeutic approach by targeting argininosuccinate lyase (ASL). ASL is transcriptionally induced by endoplasmic reticulum stress and is over...

members of cyperacea family are among the common host species of rust fungi. to our knowledge, till now seven puccinia species have been recorded on cyperaceous plants in iran. of these, four species were known on carex. in present report, other rust species are reported on carex orbicularis subsp. kotschyana (boiss. & hohenacker) kukkonen. this report is based on infected specimen collected fr...

Arginine is a non-essential amino acid that modulates nitric oxide production and cancer homeostasis. In our previous study, we observed that blocking argininosuccinate lyase (ASL) attenuates tumor progression in liver cancer. However, the role of ASL in human breast cancer has been studied to a lesser degree. In the present study, we investigated the effect of targeting ASL in breast cancer. W...