Medical Mycology is first and foremost a laboratory technique manual. While each chapter begins with some explanatory text providing background on the pathogenic fungi, the bulk of the book is devoted to protocol. The text, edited by Kevin Kavanagh, covers diagnosis ofCandida infection by immunohistochemistry, techniques for identification of pathogenic fungi using transmission electron microsc...

Medical Mycology is first and foremost a laboratory technique manual. While each chapter begins with some explanatory text providing background on the pathogenic fungi, the bulk of the book is devoted to protocol. The text, edited by Kevin Kavanagh, covers diagnosis ofCandida infection by immunohistochemistry, techniques for identification of pathogenic fungi using transmission electron microsc...

Although α-1,3-glucan is a major cell wall polysaccharide in filamentous fungi, its biological functions remain unclear, except that it acts as a virulence factor in animal and plant pathogenic fungi: it conceals cell wall β-glucan on the fungal cell surface to circumvent recognition by hosts. However, cell wall α-1,3-glucan is also present in many of non-pathogenic fungi. Recently, the univers...

Fusarium graminearum is the pathogenic agent of Fusarium head blight (FHB), which is a destructive disease on wheat and barley, thereby causing huge economic loss and health problems to human by contaminating foods. Identifying pathogenic genes can shed light on pathogenesis underlying the interaction between F. graminearum and its plant host. However, it is difficult to detect pathogenic genes...

Phytophthora fragariae var. fragariae is a serious plant-pathogenic fungus causing red core disease in strawberries, resulting in a larger number of fruit produced, and the fungus has been regulated as a quarantine pest of many countries and regions. Here, we announce the genome sequence of P. fragariae var. fragariae, and this information might provide insight into the mechanism of pathogenici...

A macrolide compound known as pandangolide 1 was isolated from fungus Lambertella brunneola. The compound was purified using SiO2 column chromatography while the elucidation of its planar structure was based on the analyses of Nuclear Magnetic Resonance (NMR) spectroscopic data and Mass Spectroscopy (MS). Antifungal assay disclosed that pandangolide 1 weakly showed hyphal growth inhibition agai...

The isoprenoid farnesol was previously shown to induce morphological features characteristic of apoptosis in the filamentous fungus Aspergillus nidulans. This study demonstrates that under similar liquid media growth conditions, farnesol also triggers apoptosis in the plant pathogenic fungus Fusarium graminearum. However, unlike A. nidulans, F. graminearum spores treated with farnesol exhibited...

The growth capacity at 39 degrees C and 42 degrees C, production of hydrolytic enzymes and hemolytic activity of 21 clinical and reference strains of seven species of Candida spp were evaluated in vitro.Candida dubliniensis and Candida krusei demonstrated lower virulence potential and Candida albicans higher potential.

Fungal pathogens of plants and animals have multifarious effects; they cause devastating damages to agricultures, lead to life-threatening diseases in humans, or induce beneficial effects by reducing insect pest populations. Many virulence factors have been determined in different fungal pathogens; however, the molecular determinants contributing to fungal host selection and adaptation are larg...