نتایج جستجو برای: 246 trinitrobenzene sulfonic acid

تعداد نتایج: 753810  

Journal: :International journal of molecular medicine 2006
Einat Amit-Romach Ram Reifen Zehava Uni

Many studies dealing with trinitrobenzene sulfonic acid (TNBS) colitis in rats have been carried out referring only to the colon. In humans, ulcerative colitis (UC) can extend a variable distance into the terminal ileum in a phenomenon known as backwash ileitis (BWI). The aim of this study was therefore to examine the effect of TNBS-induced colitis on different aspects of the rat ileum and jeju...

Journal: :Han-guksikpumjeojang-yutonghakoeji 2023

Hemp (Cannabis sativa L.) seeds have recently been attracting attention as a new high-value-added food material owing to their excellent nutritional properties, and research on the development of functional materials using hemp is actively progressing. This study aimed evaluate antioxidant properties seed protein hydrolysates. Protein hydrolysates were prepared from defatted powder (HS) by enzy...

Journal: :iranian journal of basic medical sciences 0
turan karaca university of trakya, faculty of medicine, department of histology- embryology, balkan campus, 22030, edirne, turkey yesim hulya uz university of trakya, faculty of medicine, department of histology- embryology, balkan campus, 22030, edirne, turkey selim demirtas university of trakya, faculty of medicine, department of histology- embryology, balkan campus, 22030, edirne, turkey ihsan karaboga university of trakya, faculty of medicine, department of histology- embryology, balkan campus, 22030, edirne, turkey guray can university of trakya, faculty of medicine, department of gastroenterolgy, balkan campus, 22030, edirne, turkey

objective(s):in the present study, we evaluated immunological and immunomodulatory properties of royal jelly (rj) in 2,4,6 trinitrobenzene sulfonic acid (tnbs)-induced colitis in rats. materials and methods: eighteen adult female wistar albino rats were divided into three groups of six animals each: a control group that received only saline solution, a tnbs-induced colitis group, and a tnbs-col...

Journal: :research in pharmaceutical sciences 0
a motavallian-naeini s andalib m rabbani p mahzouni m afsharipour m minaiyan

trinitrobenzene sulfonic acid (tnbs)-induced colitis is one of the most common methods for studying inflammatory bowel disease in animal models. several factors may, however, affect its reproducibility, rate of animal mortality, and macroscopic and histopathological outcomes. our aim was to validate the main contributing factors to this method and compare the effects of different reference drug...

Journal: :Developmental and comparative immunology 1994
L N Ruben D R Buchholz P Ahmadi R O Johnson R H Clothier S Shiigi

Thymocyte apoptosis in adult Xenopus laevis is demonstrated on agarose gels and is quantified by propidium iodide incorporation using flow cytometry. Basal apoptotic levels are increased after in vitro exposure to a glucocorticoid, dexamethasone (DEX), and to the lectin, phytohemagglutinin (PHA). To determine the role that newly introduced antigenic determinants may play in this regard, a reper...

Journal: :Free radical biology & medicine 1992
T Adachi H Ohta K Hayashi K Hirano S L Marklund

The secretory enzyme extracellular-superoxide dismutase (EC-SOD) has affinity for heparin and some other sulfated glycosaminoglycans and is in vivo bound to heparan sulfate proteoglycan. Nonenzymic glycation of EC-SOD, both in vivo and in vitro, is associated with a reduction in heparin affinity, whereas the enzymic activity is not affected. The glycation sites in EC-SOD are further studied in ...

2017
Gedson Rodrigues de Morais Lima Flavia Danniele Frota Machado Larissa Lucena Périco Felipe Meira de Faria Anderson Luiz-Ferreira Alba Regina Monteiro Souza Brito Cláudia Helena Pellizzon Clélia Akiko Hiruma-Lima Josean Fechine Tavares José Maria Barbosa Filho Leônia Maria Batista

AIM To evaluate the anti-inflammatory intestinal effect of the ethanolic extract (EtOHE) and hexane phase (HexP) obtained from the leaves of Combretum duarteanum (Cd). METHODS Inflammatory bowel disease was induced using trinitrobenzenesulfonic acid in acute and relapsed ulcerative colitis in rat models. Damage scores, and biochemical, histological and immunohistochemical parameters were eval...

2000
Atsushi Kitani Ivan J. Fuss Kazuhiko Nakamura Owen M. Schwartz Takashi Usui Warren Strober

In this study, we show that a single intranasal dose of a plasmid encoding active transforming growth factor b 1 (pCMV-TGFb 1) prevents the development of T helper cell type 1 (Th1)mediated experimental colitis induced by the haptenating reagent, 2,4,6-trinitrobenzene sulfonic acid (TNBS). In addition, such plasmid administration abrogates TNBS colitis after it has been established, whereas, in...

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