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تعداد نتایج: 10637116 فیلتر نتایج به سال:
Antioxidant and antimicrobial activities of the essential oil and n-hexane (HEE), chloroform (CHE), ethyl acetate (EAE), and methanol (MEE) extracts, respectively, from the root of Saurauia lantsangensis Hu were investigated. The GC-MS analysis revealed 39 compounds representing 96.41% of the oil containing T-muurolol (13.85%), acetophenone (7.46%), alpha-cadinol (6.26%), methyl palmitate (5.36...
OBJECTIVE To compare efficacy of indacaterol to that of fixed-dose combination (FDC) formoterol and budesonide (FOR/BUD) and FDC salmeterol and fluticasone (SAL/FP) for the treatment of chronic obstructive pulmonary disease (COPD) based on the available randomized clinical trials (RCTs). METHODS Fifteen placebo-controlled RCTs were included that evaluated: indacaterol 150 μg (n = 5 studies), ...
OBJECTIVES To assess the efficacy of three different daily doses of acetazolamide in the prevention of acute mountain sickness and to determine the lowest effective dose. DESIGN Systematic review and meta-analysis. DATA SOURCES Medline and Embase along with a hand search of selected bibliographies. No language restrictions were applied. STUDY SELECTION Randomised controlled trials assessi...
The potential of feeding a blend of 3 strains of Bacillus subtilis (Sporulin; SPR), to control Salmonella (SAL) was evaluated in broilers challenged with a strain of Salmonella Heidelberg (SH) isolated in Brazil . A total of 288 broilers were allocated to 6 treatments of 4 replicates of 12 birds each . Groups were T1) Non-challenged (NC), T2) NC fed 250 g of SPR/ton, T3) NC fed 500 g of SPR/ton...
UNLABELLED CCX282-B, also called vercirnon, is a specific, orally-administered chemokine receptor CCR9 antagonist that regulates migration and activation of inflammatory cells in the intestine. This randomized, placebo-controlled trial was conducted to evaluate the safety and efficacy of CCX282-B in 436 patients with Crohn's disease. Crohn's Disease Activity Index (CDAI) scores were 250-450 and...
Imputation as a method of creating low-density chips to high-density chips has been introduced to increase the accuracy of genomic selection in animals. In the current study, to investing imputation accuracy, three populations of mixed (scenario 1), pure (scenario 2) and mixed + pure (scenario 3) were simulated using QMSim. Two methods of imputation including Beagle and Flmpute were used fo...
Acetazolamide is used to prevent acute mountain sickness (AMS). We assessed efficacy and harm of acetazolamide for the prevention of AMS, and tested for dose-responsiveness. We systematically searched electronic databases (until April 2011) for randomized trials comparing acetazolamide with placebo for the prevention of AMS. For each dose, risk ratios were aggregated using a Mantel-Haenszel fix...
the essential oils, isolated by hydrodistillation from the leaves, seeds and rhizomes of heracleum sprengelianum (wight and arnott), collected from the western ghats of peninsula india, were analyzed by gas chromatography (gc) and gas chromatography coupled to mass spectrometry (gc–ms). the antioxidant property of these oils was tested, with and without peroxidation inducer, through the egg yol...
PURPOSE Zebularine is a DNA methyltransferase inhibitor proposed for clinical evaluation. EXPERIMENTAL DESIGN We developed a liquid chromatography/mass spectrometry assay and did i.v. and oral studies in mice, rats, and rhesus monkeys. RESULTS In mice, plasma zebularine concentrations declined with terminal half-lives (t(1/2)) of 40 and 91 minutes after 100 mg/kg i.v. and 1,000 mg/kg given ...
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