Detection of complex splice sites (SSs) and polyadenylation sites (PASs) of eukaryotic genes is essential for the elucidation of gene regulatory mechanisms. Transcriptome-wide studies using high-throughput sequencing (HTS) have revealed prevalent alternative splicing (AS) and alternative polyadenylation (APA) in plants. However, small-scale and high-depth HTS aimed at detecting genes or gene fa...

This paper describes a new class of maximally at lowpass recursive digital lters. The lters are realizable as a parallel sum of two allpass lters, a structure for which low-complexity low-noise implementations exist. Note that, with the classical Butterworth lter of degree N, which is retrieved as a special case, it is not possible to adjust the delay (or phase-linearity). However, with the mor...

Traditional continuous-time filters are of integer order. However, using fractional calculus, filters may also be represented by the more general fractional-order differential equations in which case integer-order filters are only a tight subset of fractional-order filters. In this work, we show that low-pass, high-pass, band-pass, and all-pass filters can be realized with circuits incorporatin...

Two protocols developed for the Tonal and Speech Materials for Auditory Perceptual Assessment audio compact disc are low- and high-pass filtered versions of the Northwestern University Auditory Test No. 6 (female speaker). Two experiments were performed on subjects with normal hearing to determine the needed filter characteristics of the words. In Experiment I, word-recognition performance was ...