Abstract Signomial Programming (SP) has proven to be a powerful tool for engineering design optimization, striking balance between the computational efficiency of Geometric (GP) and extensibility more general methods optimization. While techniques exist fitting GP compatible models data, no have been proposed that take advantage increased modeling flexibility available in SP. Here, new Differen...

In this study, surface features such as dimples and bumps are introduced to the of a NACA 0012 airfoil study their effect on boundary layer separation, particularly at high angles attack. Six modified airfoils were designed with spherical pyramidical shapes. A computational fluid dynamics (CFD) analysis was conducted these models subsonic flow using Ansys Fluent. The used Shear Stress Transport...

This paper focuses on aerodynamic analysis over a 3D cambered wing with dimple-like surface modification. Application of the golf ball dimples airfoils is predicted to be good alternative for drag reduction. A allows smooth and controlled flight. Models wings based NACA 2412 airfoil were created investigate dimple effect. comparative study carried out between models inward outward at 50% chord ...

Abstract Dynamic stall, which has a significant effect on the aerodynamic performances of dynamic airfoils, is closely related to physics stall vortex (DSV). The DSV NACA 0012 airfoil was experimentally studied using unsteady pressure measurements with high time accuracy. experimental Reynolds number Re = 1.5 × 10 6 , and reduced frequency k 0.069. propagation field during process analyzed in d...

Ionizing radiation is known to cause tissue damage in biological systems, mainly due to its ability to produce reactive oxygen species (ROS) in cells. Many thiol antioxidants have been used previously as radioprotectors, but their application has been limited by their toxicity. In this investigation, we have explored the possible radioprotective effects of a newly synthesized thiol antioxidant,...

The contributions of electrogenic sodium/calcium exchange current ( I NaCa), calcium-activated chloride conductance [ I Cl(Ca)], and calcium-activated nonselective cation conductance to delayed afterdepolarizations (DAD) were examined. Nonselective cation channels were absent in canine M cells, since inhibition of I NaCa and I Cl(Ca)eliminated all calcium-activated currents without abolishing c...

Contrast-induced nephropathy (CIN) is a leading cause of hospital-acquired acute kidney injury (AKI) due to apoptosis induced in renal tubular cells. Our previous study demonstrated the novel N-acetylcysteine amide (NACA); the amide form of N-acetyl cysteine (NAC) prevented renal tubular cells from contrast-induced apoptosis through inhibiting p38 MAPK pathway in vitro. In the present study, we...

The antioxidant potential of N-acetylcysteine amide (NACA), also known as AD4, was assessed by employing different in vitro assays. These included reducing power, free radical scavenging capacities, peroxidation inhibiting activity through linoleic acid emulsion system and metal chelating capacity, as compared to NAC and three widely used antioxidants, alpha-tocopherol, ascorbic acid and butyla...

Oxidative stress plays an important role in neuronal cell death associated with many different neurodegenerative conditions such as cerebral ischemia and Parkinson's disease. Elevated levels of glutamate are thought to be responsible for CNS disorders through various mechanisms causing oxidative stress induced by a nonreceptor-mediated oxidative pathway which blocks cystine uptake and results i...

This study introduces a framework for the design and implementation of acoustic black holes (ABHs) in airfoils. A generalized multi-parameter damped-ABH generation function is mapped onto NACA series Representative geometries uniformly distributed baseline, all with same mass structure damping are fabricated using multi-material PolyJet 3D printing. Laser Doppler vibrometer measurements along a...