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Tyrosinase was the first melanoma-associated antigen shown to be recognized by CD4+ T cells. In this study, we have identified two HLA-DRB1*0401-restricted peptides recognized by these T cells: Ty 56-70 and Ty 448-462. As with many of the MHC class I-restricted melanoma epitopes, both are nonmutated self peptides that have intermediate and weak MHC binding affinities, respectively. Mutated and ...

Encarnación Castro-Páez y Gonzalo Cruz Andreotti (eds. científicos), Geografía cartografía de la Antigüedad al Renacimiento. Estudios en honor Francesco Prontera, Alcalá Henares, Editorial Universidad Alcalá-Editorial Sevilla, 2020, 462 pp.

Neural networks are organized in committees to improve the correctness of the decisions created by artificial neural networks (ANN’s). In the classification of human chromosomes, it is accustomed to use multilayer perceptrons with multiple (22-24) outputs. Because of the huge number of synaptic weights to be tuned, these classifiers cannot go beyond a level of 92% overall correctness. In this s...

Running head: 1 An R2R3-MYB gene regulates pungency in chili pepper 2 3 Corresponding author: 4 Neftalí Ochoa-Alejo 5 Mailing address: Departamento de Ingeniería Genética de Plantas, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-Unidad Irapuato). Km. 9.6 Libramiento Norte Carretera Irapuato-León; Apartado Postal 629; 36821-Irapuato, Gto., México. ...

1 Title: Representation of the spatial relationship among object parts by neurons in macaque inferotemporal cortex Authors: Yukako Yamane, Kazushige Tsunoda, Madoka Matsumoto, Adam N. Phillips, and Manabu Tanifuji Affiliation: 1 Laboratory for Integrative Neural Systems, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan 2 Division of Biological Sciences, Graduate Sc...