HYDROXYUREA is a cytotoxic drug which has recently been investigated as a therapeutic agent in a number of malignant conditions, e.g. cancer of the head and neck (Beckloff, 1967), and leukaemia especially chronic myeloid leukaemia (Malpas, 1967; Weil and Tanzer, 1967). It is not a new compound but has only recently been screened for activity against cancer. It is believed that the activity of h...

Rapidly expanding technologies in the fi eld of virology, identifi cation of novel viral agents, and the 2005 report (8th edition) of the International Congress of Taxonomy of Viruses (ICTV) addressing reclassifi cation of several viruses generated the 20% new material in Mahy’s 4th edition of The Dictionary of Virology. The previous edition of this book was published in 2001; the 2009 edition ...