Objective. The aim of our study was to examine the pattern benzodiazepines' use in young adults municipality Bijelo Polje, Montenegro. Methods. investigation conducted as a cross-sectional which involved 80 subjects both gender aged between 18 and 40 years. data were collected using self-administered survey questionnaire, consisted 14 closed ended questions related sociodemographic characterist...

Benzodiazepines (BDZs) are the chemicals having the versatile medicinal values. These are the type of psychotropic drug, that is, they concern the mind and can amend frame of mind. Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) and are subsequently used therapeutically as anxiolytics, tranquilizers, hypnotics, anticonvulsants in epilepsy and centrally ...

BACKGROUND Benzodiazepines are frequently prescribed to patients with drug use disorders. However, it has previously been difficult to distinguish whether this frequent prescribing was due to underlying psychiatric disorders or inappropriate prescribing. In a nationwide cohort study, we investigated the prescribing of benzodiazepines to patients with drug use disorders in connection with treatm...

BACKGROUND/AIM The analysis of drug prescribing in general practice in Serbia showed that the use of benzodiazepines is most frequently associated with hypertension. The aim of this study was to establish the correlation of the characteristics of patients with hypertension to antihypertensive drug therapy, and the intake of benzodiazepines. METHODS A special questionnaire was used for intervi...

BACKGROUND This article aims at determining the place of benzodiazepines in the current treatment of anxiety disorders in opposition to antidepressants, neuroleptics and anticonvulsants. Belgium and France are the only two European countries which prescribe the most benzodiazepines despite the dissuasion of the international guidelines (NICE) issued in the nineties concerning the high risk of d...

a high performance liquid chromatographic method with ultra violet detection for simultaneous analysis of six benzodiazepines (bzds) (chlordiazepoxide, diazepam, clonazepam, midazolam , flurazpam and lorazepam) has been developed for forensic screening of adulterated non-alcoholic drinks. samples were analyzed after a simple procedure for preparation using ph adjustment and filtering. isocratic...

Benzodiazepines are widely prescribed for a variety of conditions, particularly anxiety and insomnia. They are relatively safe and, with overdose, rarely result in death. However, used chronically, benzodiazepines can be addicting. These agents are often taken in combination with other drugs of abuse by patients with addiction disorders. In such patients, alternatives to benzodiazepines may be ...

OBJECTIVES Benzodiazepines have been associated with an increased incidence of infections, and mortality from sepsis, in the critically ill. Here, we determined the effect of community use of benzodiazepines on the occurrence of, and mortality following, pneumonia. METHODS A nested case-control study using 29 697 controls and 4964 cases of community-acquired pneumonia (CAP) from The Health Im...

BACKGROUND Benzodiazepines are frequently prescribed in patients with Alzheimer's disease. Unfortunately, studies evaluating their benefits and risks in these patients are limited. METHODS Clinical trials focusing on the effect of benzodiazepines on cognitive functions, disease progression, behavioral symptoms, sleep disturbances, and the general frequency of benzodiazepine use were included ...

Numerous literature data indicates that benzodiazepines inHuence neuronal activity in various sections of centrai nervous system, from spinal cord to the brain stem up to neocortex. I t was shown t ha t benzodiazepines increase t be presynaptic inhihition in the spinal cord [1-3] and various types of postsynaptic inhibition in the cerebellum [4] and nigrostriatal system [5]. Since these types o...