The implementation of cost-effective and sustainable biorefineries to substitute the petroleum-based economy is dependent on coupling production bioenergy with high-value chemicals. For this purpose, US Department Energy identified a group key target compounds be produced from renewable biomass. Among them, 5-hydroxymethylfurfural (HMF) can obtained by dehydration hexoses present in biomass an ...

Despite the importance of epigenetic regulation in neurological disorders, little is known about neuronal chromatin. Cerebellar Purkinje neurons have large and euchromatic nuclei, whereas granule cell nuclei are small and have a more typical heterochromatin distribution. While comparing the abundance of 5-methylcytosine in Purkinje and granule cell nuclei, we detected the presence of an unusual...

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background: the aberrant expression of dickkopf-1 (dkk1), triose phosphate isomerase (tpi) and fatty acid binding-protein 5 (fabp5) in lung cancer tissues and their presence in secretome of lung cancer cell lines were reported. here, serum levels of these molecules in lung cancer patients were compared to those in a healthy control group. materials and methods: the patients’ group consisted of ...