نتایج جستجو برای: 5 oxadiazole

تعداد نتایج: 1216478  

Journal: :Electrochimica Acta 2021

An oxadiazole derivative with functional groups favouring its adsorption on copper surface, namely 5-(4-pyridyl)-1,3,4-oxadiazole-2-thiol, has been explored as potential inhibitor of corrosion in 3.5 wt.% NaCl. Electrochemical evaluation by electrochemical impedance spectroscopy, potentiodynamic polarization and SVET reveals high inhibition efficiencies. Surface microscopy inspection spectrosco...

Journal: :Acta Crystallographica Section E Structure Reports Online 2008

Journal: :Acta Crystallographica Section E Structure Reports Online 2013

Journal: :Journal of medicinal chemistry 2015
Edward Spink Derong Ding Zhihong Peng Marc A Boudreau Erika Leemans Elena Lastochkin Wei Song Katerina Lichtenwalter Peter I O'Daniel Sebastian A Testero Hualiang Pi Valerie A Schroeder William R Wolter Nuno T Antunes Mark A Suckow Sergei Vakulenko Mayland Chang Shahriar Mobashery

The structure-activity relationship (SAR) for the newly discovered oxadiazole class of antibiotics is described with evaluation of 120 derivatives of the lead structure. This class of antibiotics was discovered by in silico docking and scoring against the crystal structure of a penicillin-binding protein. They impair cell-wall biosynthesis and exhibit activities against the Gram-positive bacter...

2013
Arvind Kumar Singh M Lohani R Parthsarthy

A series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (C1- C7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. All the synthesis compounds have been characterized by (1)HNMR, IR and Mass spectral data. The compounds were purif...

2013
Zafer Asim KAPLANCIKLI Mehlika Dilek ALTINTOP Rasime DEMIREL

Some oxadiazole derivatives were tested in vitro against Aspergillus parasiticus, Aspergillus flavus, Aspergillus niger, Fusarium solani, Fusarium moniliforme and Stachybotrys chartarum. All compounds showed the highest antifungal activity against S. chartarum. Among these compounds (3a-j), compounds 3a, 3c, 3d, 3e, 3i, 3j exhibited the same level of antifungal activity against all tested mold ...

Journal: :Journal of Molecular Modeling 2021

In this study, 32 energetic compounds were designed using oxadiazoles (1,2,5-oxadiazole, 1,3,4-oxadiazole) as the parent by inserting different groups well changing bridge between parent. These had high density and excellent detonation properties. The electrostatic potentials of analyzed functional theory (DFT). structure, heat formation (HOF), density, performances (detonation pressure P, velo...

2012
A. Muralikrishna M. Kannan V. Padmavathi A. Padmaja R. Krishna

In the title compound, C(18)H(16)ClN(3)O(5)S(2), the dihedral angles between the oxadiazole ring and the phenyl and chloro-benzene rings are 23.4 (2) and 45.4 (2)°, respectively. The C-S-N-C and C(ox)-C-S-C (ox = oxadiazole) torsion angles are 89.3 (5) and -69.1 (3)°, respectively. A short intra-molecular C-H⋯O contact closes an S(6) ring. In the crystal, mol-ecules are linked by N-H⋯O hydrogen...

Journal: :Acta Crystallographica Section E Structure Reports Online 2008

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