Hormesis is an adaptive response of living organisms to a moderate stress. However, its biomedical implication and molecular mechanisms remain to be intensively investigated. Panaxatriol saponins (PTS) is the major bioactive components extracted from Panax notoginseng, a widely used herbal medicine for cerebrovascular diseases. This study aims to examine the hormetic and neuroprotective effects...

Subclinical hypothyroidism (SCHT) is common, with an occurrence of up to 10% of the adult population and defined biochemically only by elevated TSH and normal T4. SCHT affects negatively on lipid and carbohydrate metabolism increasing the risk of ischemic heart disease, affects negatively on cardiac performance and have a close correlation with renal function. The aim of this study is to compar...

TCP performance degrades with increasing round trip time (rtt) due to longer slow start periods and slower rate of increase of the congestion window. The proposed, PTS (proxy transport service) is an active network based service, that can improve the end-to-end performance of TCP connections with large rtt’s. PTS also reduces the response time of TCP to congestion and can be used by other activ...

Introduction: Autonomic heart rate (HR) control evaluated by means of HR variability measures has been widely accepted as important information of cardiovascular function being a marker of sudden death. Methods: Polysomnography was performed in 405 CAD pts (mean age 60.7 yr.) pts, including 200 pts with CHF (mean age 63.4 yr.). Sleep apnea syndrome (SAS) was observed in 46 pts (mean age 64.2 yr...

Partial Transmit Sequence (PTS) technique is an attractive technique for peak-to-average power ratio (PAPR) reduction of orthogonal frequency division multiplexing (OFDM) signals. However, optimum PTS (OPTS) requires an exhaustive search over all combinations of allowed phase weighting factors, resulting in high computational complexity. In this paper, we propose an Alternate Optimised Grouping...

Public Transport system (PTS) is an important and an essential part of urban and rural dwellers. PTS enables a smooth mobility of people and goods. Without PTS no city can improve the standard of living of the people and can make progress. As the population continues to increase, many problems arise which make the PTS an unreliable and inefficient service provider. So, providing a good PTS is r...

Background: The major limitation of the anthracyclines (AC) class of cancer chemotherapeutic drugs is progressive cardiotoxicity. Currently, patients receiving AC are monitored by echocardiographic measurement of shortening fraction (SF). Other indices, though more sensitive, are technically difficult to obtain. There is a need for a sensitive and rapid biomarker to detect cardiac injury in the...

AIMS To evaluate the effect of beta-blockers in children with long QT syndrome (LQTS) we reviewed the outcome of 122 patients (pts). METHODS LQTS was diagnosed in 24 neonates and in 98 pts aged 0.5-15 years. Diagnosis was made because of syncope in 51 pts, bradycardia in 10 neonates and family history in 61 pts. The longest QTc ranged from 400 to 700 ms. Thirteen pts had 2:1 atrioventricular ...

CRA1008 Background: Decision making on systemic treatment of women with metastatic breast cancer is based on features like estrogen receptor (ER), progesterone receptor (PgR), and HER2 status assessed on the primary tumor. We evaluated the concordance of receptor status between primary tumor and liver metastases (mts) and its impact on treatment choice. METHODS We retrospectively analyzed a d...

BACKGROUND Post-thrombotic syndrome (PTS) is a chronic complication of deep venous thrombosis (DVT). OBJECTIVES To determine the risk of PTS after DVT and to assess risk factors for PTS. METHODS Patients were recruited from the Multiple Environmental and Genetic Assessment (MEGA) study of risk factors for venous thrombosis. Consecutive patients who suffered a first DVT of the leg were inclu...