UreG is one of the accessory proteins of urease in plants. In this study, a gene encoding an UreG consisting of 363 amino acids from Arabidopsis thaliana was isolated. The AtUreG gene was expressed in Escherichia coli BL21 as a GST fusion protein. The GST-AtUreG fusion protein was induced and purified under the optimized culturing conditions of 0.2 mM IPTG and 25°C for 5 h. Western blot analysi...

An 82-year-old female with a history of situs inversus totalis visited our hospital with complaints of abdominal pain and fever for 2 days. She had history of diabetes mellitus, cerebral infarction, and Alzheimer’s disease, and underwent Billroth-ll (B-II) gastrectomy due to stomach cancer 15 years previously. General appearance was acute ill looking and there was tenderness on right upper quad...

Institute of Zoology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland Neurobiology Section, Biological Sciences Division, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA Corresponding author. Tel: +41 44 635 4840; Fax: + 41 44 635 6879; E-mail: [email protected] Corresponding author. Tel: +1 858 534 7212; Fax: +1 858 534 ...

Dysregulation of microRNA expression is involved in several pathological activities associated with gastric cancer progression and chemo-resistance. However, the role and molecular mechanisms of miR-363 in the progression and chemo-resistance of gastric cancer remain enigmatic. In this study, we validated that miR-363 expression was higher in gastric cancer tissues than in adjacent normal tissu...

The miR-106a~363 cluster encodes 6 miRNAs on the X-chromosome which are abundant in blood cells and overexpressed in a variety of malignancies. The constituent miRNA of miR-106a~363 have functional activities in vitro that are predicted to be both oncogenic and tumor suppressive, yet little is known about their physiological functions in vivo. Mature miR-106a~363 (Mirc2) miRNAs are processed fr...