0

cladribine, an analogue of deoxyadenosine, is highly toxic for both non-dividing and proliferating cells and has shown activity in the treatment of several malignancies. therefore, the aim of the present study is to investigate the cytotoxicity effect of cladribine (2-cda) on the breast cancer cell line, mcf-7 (estrogen receptor positive, er+). mtt assay, annexin v-fluorescein/pi and hoechst 33...

several attempts have so far been made in the search of new anticancer agents of plant origin. some studies have reported that different species of pine genus possess cytotoxic activities against various cancer cell lines. in the present study, we evaluated the cytotoxic effects of pinus eldarica bark and leaf extracts or leaf essential oil on hela and mcf-7 tumor cell lines. hydroalcoholic and...

fragrant species of the genus salvia have been attributed many medicinal properties, which include anticancer activity. in the present study, cytotoxic properties of total methanol extract of salvia chloroleuca rech. f. & aellen and its fractions were investigated on mcf-7, a breast carcinoma cell line. malignant and non-malignant cells were cultured in rpmi medium and incubated with different ...

objective: perovskia abrotanoides karel, belongs to the family lamiaceae and grows wild alongside the mountainous roads inarid and cold climate of northern iran. the anti-tumor activity of p. abrotanoides root extract has been shown previously. this study was designed to examine in vitro anti-proliferative and pro-apoptotic effects of flower extract of p. abrotanoides on mcf-7 and hela cell lin...

t cell acute lymphoblastic leukemia (all) is an invasive disease with a higher incidence in children and adolescents. in terms of immunophenotype, t-all is positive for cd2, cd7, cd34 and hla-dr, and the level of these markers is increased with increasing age. in addition, the myeloid markers (cd13, cd33) are sometimes expressed in t-all. in this study, we introduce a rare case of a 28-year-old...