The X-linked McLeod neuroacanthocytosis syndrome strongly resembles Huntington's disease and has been reported in various countries world-wide. Herein, we report two Chilean brothers with predominant psychiatric features at disease onset including schizophrenia-like psychosis and obsessive compulsive disorder. Molecular genetic analysis revealed a small deletion in the XK gene (938-942delCTCTA)...

We studied the bias and precision of serum cholesterol analysis by physician's office analyzers. Total imprecision (CV range, %) for analysis of serum pools was: Abbott Vision 1.5%-1.9%; Ames Seralyzer 3.9%-4.5%; BMD Reflotron 2.3%-3.8%; Chrometrics Cholesterol Test System 2.3%-2.8%; Kodak DT-60 1.6%-2.2%. The Ames Seralyzer exhibited an excessive between-run component of variation. We collecte...

OBJECTIVE Cultural portrayals of physicians suggest an unclear and even contradictory role for humility in the physician-patient relationship. Despite the social importance of humility, however, little empirical research has linked humility in physicians with patient outcomes or the characteristics of the doctor-patient visit. The present study investigated the relationship between physician hu...

Abstract Aim Secondary prevention medication is recognised to reduce cardiovascular events in patients with established atherosclerotic disease; the form of antiplatelet and lipid-lowering therapy. Yet a lack consensus between European Society Vascular Surgery (ESVS) (Wanhainen et al., 2019) NICE guidelines (NICE, 2021b; a) (Saratzis 2017). Abdominal aortic aneurysm (AAA) manifestation peripher...

Abstract Background Lamin A (LMNA) protein is one of the main constituents nuclear lamina. Pathogenic variants LMNA gene have been demonstrated to be linked a wide spectrum disorders, including cardiac diseases. The first reported heart disease was dilated cardiomyopathy (DCM), in form typically characterized by presence conduction disorders and high incidence sudden death (SCD) disrespectfully...

conclusions primary extracranial meningiomas (pems) without intracranial origin are very rare and because of their slow growing nature are initially managed by primary care physicians. case presentation we report a case of slowly progressing extracranial meningioma that was presented in a young adult woman. the tumor was asymptomatic but large enough to cause cosmetic discomfort. patient underw...