CONTEXT AND OBJECTIVE Studies using radionuclides are the most appropriate method for estimating renal function. Dimercaptosuccinic acid chelate labeled with technetium-99m (99mTc-DMSA) is the radiopharmaceutical of choice for high-resolution imaging of the renal cortex and estimation of the functional renal mass. The aim of this study was to evaluate a simplified method for determining the abs...

PURPOSE With growing interest in early imaging, the aim of our study was to define the most practical modality for routine clinical use for the diagnosis of acute pyelonephritis (APN). We compared the sensitivity of enhanced computerized tomography (CT), dimercaptosuccinic acid (DMSA) scintigraphy, and Doppler ultrasonography (DUS) by using clinical findings as the standard of reference. MATE...

A 3 years old boy with a history of surgery for orchidopexy was admitted to our hospital with fever and abdominal pain. Clinical examination and laboratory investigations revealed urinary tract infection with renal involvement. Ultrasonography demonstrated a solitary left kidney and raised the suspicion of a fusion anomaly. Voiding cystography disclosed grade III vesicoureteral reflux and tec...

BACKGROUND The reliable method for determination of identity and radiochemical purity (RCP) is of great importance in radiopharmaceutical development. This is especially relevant when more than one form of radiometal/ligand complex can be formed during radiolabelling, such as complexes of 99mTc or 188Re with meso-2,3-dimercaptosuccinic acid (DMSA), where depending on the pH, metal can occur eit...

OBJECTIVES To examine the value of an intravenous urogram (i.v.U) in patients with abnormal differential (99m)Tc dimercaptosuccinic acid (DMSA) uptake without scarring or ultrasound abnormality. STUDY DESIGN Forty patients (age 0-19 years) were identified over a two year period in whom the differential renal uptake was >10%, who had smooth renal outlines, and had no evidence of scarring. All ...

The purpose of this guideline is to offer to the nuclear medicine team a framework that could prove helpful in daily practice. This guideline contains information related to the acquisition, processing, interpretation and indications for 99m Tc-DMSA scintigraphy in children. This guideline summarizes the views of the Paediatric Committee of the European Association of Nuclear Medicine. It shoul...

DMSA (meso-2,3-dimercaptosuccinic acid) adalah suatu senyawa dengan gugus sulfhydryl yang mampu berikatan secara chelation berbagai logam berat. Awalnya dimanfaatkan sebagai antidotum keracunan berat, namun seiring berjalannya ilmu pengetahuan, berhasil ditandai menggunakan Tc-99m Pertechnetate dan dimaanfaatkan luas dalam bidang kedokteran nuklir. scan telah digunakan nefrourologi, terutama un...

background renal scintigraphy with technetium 99m labeled dimercaptosuccinic acid (99mtc-dmsa) is a traditional imaging technique commonly used to detect renal scar in patients with probable vesicoureteral reflux (vur) and/or urinary tract infection (utis). we determined whether normal results of dmsa renal scan obviate the need for voiding cystourethrography (vcug) in evaluating children with ...