Pixon noise reduction was applied to 18 planar images, six each from 99mTc-methylene diphosphonate (99mTc-MDP), 67Ga citrate (67Ga), and (123)I-metaiodobenzylguanidine ((123)I-MIBG) studies. Pixon processing increased patient signal-to-noise ratio, 6.8-11.8 fold. Three specialists preferred processed images 44 of 54 times with good agreement (87%). Most (9/10, p<0.02) of the null and negative p...

We present a case of a 15-year-old boy with osteoblastic osteosarcoma of the left distal femur. The patient was referred to bone scan for initial staging. On planar bone scan, there is increased uptake of 99mTc-MDP (99mTc-methylene diphosphonate) in the left distal femur. There are also multiple sites of abnormal tracer uptake projecting to the thoracic cage, initially assumed to be localized i...

Stanford University, Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, USA Here we prospectively compared the combined 18F NaF/18F FDG PET/ MRI against 99mTc-MDP in patients with breast and prostate cancers. Twelve patients referred for 99mTc-MDP bone scans were prospectively enrolled from Oct 14 Jan 15. The cohort included 6 men with prostate cancer and 6 women with ...

Bone scan was performed a 77 years old man with prostatic carcinoma. The planar 3h 99mTc-methylenediphosphonate (MDP) whole-body bone scan did not reveal skeletal metastases. However, on the anterior view, unexpected, large, round shaped activity in the liver projection was noted (Panel A). Further investigation disclosed that the patient had been operated for hepatic hemangioma thirty years ag...

Purpose: To assess the role of 18F-NaF PET/CT in detection metastatic bone disease compared to 99mTc-MDP scan (+/-SPECT/CT). Methods: 64 adult patients with locally advanced primary tumor were enrolled this study. All underwent pretherapy and scan. Results: Among revealed positive metastases 26 patients, only 19 them have results scan, while remaining 7 falsely negative On other hand diagnosed ...

A case of a woman aged 46 years with signs of rhabdomyolysis and acute renal failure is presented. Coxsackie serum test was positive. Increased uptake of Technetium-99m methylene diphosphonate (99mTc-MDP) by muscles of thighs and calves was observed. After 1 year no increased accumulation of radiotracer in the muscles was found.

Although extraosseous accumulations of 99mTc phosphate complexes are phenomena which can often be seen, no case showing extraosseous accumulation to brain tumor on SPECT has been reported. We report here two cases of primary brain tumor showing extraosseous accumulation of 99mTc phosphate in bone SPECT. 201Tl SPECT also showed increased 201Tl uptake by the tumor. Comparing bone SPECT with 201Tl...

Background/Aim. There is a constant and dramatic in-crease in hip knee prosthetic implantations worldwide. However, decrease the percentage of failed (infected) not significant (0.5% up to 2%). The real challenge whether joint loosening was caused by aseptic inflammation or infection. aim present study attempt distinguish sterile from infection patients with painful joint. Another objective det...

Background: The aim of this study to assess the role of 99mTc-HMPAO leucocyte scintigraphy combined with 99mTcMDP bone scintigraphy in the diagnosis of the diabetic foot infection. Methods: 50 diabetic patients with suspected osteomyelitis were included. The HMPAO-Leucocytes/MDP scan was considered to be consistent with osteomyelitis when the HMPAOLeucocytes uptake was concordant with MDP bone ...