A method is described for analysis of nickel in serum and heparinized blood. After the sample has been subjected to protein precipitation with nitric acid and heat, nickel in the protein-free extract is measured by electrothermal atomic absorption with Zeeman background correction. The method is more sensitive, rapid, and convenient than previous techniques, and less subject to nickel contamina...

The dissolution, intestinal absorption and presystemic metabolism of a drug depend on its physicochemical characteristics but also on numerous physiological (e.g. gastrointestinal pH, volume, transit time, morphology) and biochemical factors (e.g. luminal enzymes and flora, intestinal wall enzymes and transporters). Over the past decade, evidence has accumulated indicating that these factors ma...

Calcium absorption efficiency and bone mineral mass are increased in adolescents who regularly consume inulin-type fructans (ITF). The mechanism of action in increasing absorption is unknown but may be related to increased colonic calcium absorption. We conducted a study in young adults designed to evaluate these mechanisms with a kinetic technique using (42)Ca orally and (46)Ca dosed i.v. Thos...

In this paper toxicokinetics was examined. Chemical distribution, absorption and elimination in the living organism were investigated. The aim of this paper kinetic of toxic substance during exposure in a biological system was studied. Several toxicokinetic models using physiological and biochemical parameters were derived. Physiologically based toxicokinetic models and similar pharmacokinetic ...

the aim of this study was to evaluate the physiological and morphological characteristics of narcissus tazatta in response to benzyl adenine (ba) and nano-potassium fertilizer. this experiment was done as factorial with two factors of benzyl adenine hormone and nano-potassium fertilizer in a completely randomized design with ten replications.  benzyl adenine in four levels (0, 500, 750 and1000 ...

Nutrient needs increase during pregnancy and lactation to support fetal growth and milk synthesis, respectively. Physiological adjustments that are made to meet those needs alter the fraction of ingested nutrient retained, or the bioavailability. Using stable isotopes as tracers, we measured calcium, zinc and selenium homeostasis in women during reproduction. The physiological response, and the...

When Nereis eggs are exposed to radiations from a tube of radium emanation, the walls of which absorb all the alpha-rays, the resulting physiological change is produced by rays having a coefficient of absorption of the order of 23.9 cm.(-1) This fact indicates that the physiological effect is due almost exclusively to beta-rays. The gamma-rays alone can produce the reaction. To produce equivale...

In this paper, we discuss findings from a study that used panoramic video-based virtual environments (PVVEs) to induce self-reported anger. The study assessed "immersiveness" and physiological correlates of anger arousal (i.e., heart rate, blood pressure, galvanic skin response [GSR], respiration, and skin temperature). Results indicate that over time, panoramic video-based virtual scenarios ca...

We hereby report on the design of a set-up combining micro-resonance Raman and absorption spectroscopy with a microfluidic system. The set-up enabled us to study the nerve globin of Aphrodite aculeata in the functional isolated nerve cord under varying physiological conditions for extended periods of time. The oxygenation cycle of the organism was triggered by utilizing the microfluidic system ...

The clinical implications of calcium deficiency include rickets, poor bone mass accrual as well as abnormal foetal programming during pregnancy, poor peak bone mass due to poor accrual in childhood and adolescence, postmenopausal osteoporosis and osteoporosis of the elderly. Serum calcium is maintained within a narrow normal range, chiefly by resorption from the skeleton and alteration of urina...