Anecdotal and uncontrolled studies have suggested that nonsteroidal anti-inflammatory drugs produce false-positive results in immunoassay urine tests for some drugs of abuse. This study was performed in 60 volunteers who took ibuprofen as either a single 400-mg dose, or 200 mg three times a day, or 400 mg three times a day, and in 42 patients taking ibuprofen, naproxyn, or fenoprofen in therape...

OBJECTIVES Prevalence of opioid addiction has alarmingly increased over the recent years. In South Asian region alone there are more than 10 million opioid abusers amounting to 2% of world population. Detoxification remains to be the first step for the successful treatment of opioid addiction. The present study was carried out to compare the relative efficacy and safety of buprenorphine -naloxo...

INTRODUCTION An increasingly important issue in the Polish population is drug abuse. It leads to extensive damage of parenchymal organs, including kidney. Establishing early markers of organ damage and their monitoring during rehabilitation therapy is therefore of pivotal importance. This study evaluated the utility of highly specific and selective markers (NGAL, IL-18, a and π-GST isoenzyme, a...

Athletes, like others, use recreational and lorillicit psychoactive drugs. However, many athletes also use drugs to enhance their training or performance, including an array of bizarre and exotic substances. Although the majority of these substances are not psychoactive, they may be abused by athletes. Some of these substances, such as anabolic steroids and human growth honnone, are referred to...

Copyright © 2013, Zahedan University of Medical Sciences; Published by Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. There is a close relationship between drug abuse and crime. Drug abusers commit crime...

Drug use is driven by principles of reinforcement and is sensitive to influences in the environmental context in which it occurs. Although a wide range of factors has been shown to directly influence the reinforcing effects of commonly abused drugs, 2 general types include pharmacological and nonpharmacological factors. Both can assert a powerful impact on a drug's reinforcing effects and, ther...

Adult diseases cause signifi cant pediatric morbidity. Eleven percent of women of childbearing age are current illicit drug users, and 5% of pregnant women selfreport drug use during pregnancy, which is no doubt an underestimate of the true prevalence. Opiates are the second most common class of abused drugs, after marijuana. Despite the commonly held belief that most opiates are street drugs, ...

A case is presented of a young competitive body-builder who abused anabolic steroid drugs and developed profound symptomatic hypogonadotrophic hypogonadism. With the help of prescribed testosterone (Sustanon) he stopped taking anabolic drugs, and later stopped Sustanon also. Hypogonadism returned, but was successfully treated with weekly injections of human chorionic gonadotropin for three mont...

116 CLINICAL CHEMISTRY, Vol. 41, No. 1, 1995 drugs in full-scan and selected.ion monitoring modes. Clin Chem 1994;40:216-20. 2. Doolittle MH, Lincoln K, Graves SW. Unexplained increase in serum digoxin: case report. Clin Chem 1994;40:487-92. 3. Critchfield GC, Wilkins DG, Loughmiller DL, Davis BW, Rollins DE. Antibody-mediated interference of a homogeneous immunoassay. J Anal Toxicol 1993;17:69...