BACKGROUND We performed a meta-analysis of cholinesterase inhibitors for patients with Lewy body disorders, such as Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies. METHODS The meta-analysis included only randomized controlled trials of cholinesterase inhibitors for Lewy body disorders. RESULTS Seventeen studies (n = 1798) were assessed. Cholinesterase inhib...

Dementia associated with probable Alzheimer's disease (AD) is one of the most common types of dementia. Patients with AD often have cholinergic deficits in association with the disease. The cholinesterase inhibitors donepezil hydrochloride, galantamine hydrobromide, and rivastigmine tartrate are the current mainstays of symptomatic treatment for patients with AD. In clinical trials for all thre...

The crude extract of mangrove plant Rhizophora mucronata was prepared in this present work. The extract was testified for its anti-mosquito larvicidal property against two species of mosquito viz: Anopheles stephensi and Aedes aegypti. The 48 hours exposure of various dilutions of 100, 200, 300, 400, 500 ppm were given to the III to IV instar larval population. Percentage mortality data was ana...

Organophosphorous compounds have been employed as pesticides and chemical warfare nerve agents. Toxicity of organophosphorous compounds is a result of excessive cholinergic stimulation through inhibition of acetyl cholinesterase. Clinical manifestations include cholinergic syndromes, central nervous system and cardiovascular disorders. Organophosphorous pesticide poisonings are common in develo...

Background: Tert-butyl mercaptan is one of the frequently used odorants derived from natural gases. It has been declared as a health hazard by the Occupational Safety and Health Administration (OSHA) in the USA. There is not much information available about the mercaptans long-term toxicity secondary to occupational exposure. This study was conducted to evaluate the oxidative stress caused by m...