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One of the cyr 1 mutants (cyr 1-2) in yeast produced low levels of adenylate cyclase and cyclic AMP at 25 degrees and was unable to derepress acid phosphatase. Addition of cyclic AMP to the cyr1-2 cultures elevated the level of repressible acid phosphatase activity. The bcy1 mutation, which suppresses the cyr1-2 mutation by allowing activity of a cyclic AMP-independent protein kinase, also allo...

In the rat, some phthalates alter sexual differentiation at relatively low dosage levels by altering fetal Leydig cell development and hormone synthesis, thereby inducing abnormalities of the testis, gubernacular ligaments, epididymis, and other androgen-dependent tissues. In order to define the dose-response relationship between di(2-ethylhexyl) phthalate (DEHP) and the Phthalate Syndrome of r...

in this paper‎, ‎an efficient dropping criterion has been used to compute the iul factorization obtained from backward factored approximate inverse (bfapinv) and ilu factorization obtained from forward factored approximate inverse (ffapinv) algorithms‎. ‎we use different drop tolerance parameters to compute the preconditioners‎. ‎to study the effect of such a dropping on the quality of the ilu ...