BACKGROUND Acne vulgaris is a common skin condition that affects 8 out of 10 people. It varies from mild to severe, and different treatments target various aspects of the disease. Propionibacterium acnes, one of the culprits involved in the pathogenesis of acne vulgaris, is the main target of all major medical treatments used. Studies conducted in recent years have shown favorable effects withi...

Interleukin-8 (IL-8) is a well-known inflammatory chemokine and suggested to be involved in the development of acne vulgaris. This study investigates IL-8 plasma levels in acne patients and healthy controls and the molecular basis for the regulation of the IL-8 gene in a Pakistani population. Patients with acne vulgaris (n = 264) and healthy individuals (n = 264) were enrolled in this investiga...

The relationship between diet and acne is highly controversial. Several studies during the last decade have led dermatologists to reflect on a potential link between diet and acne. This article presents the latest findings on a potential impact that diet can have on pathogenesis of acne vulgaris. The association between diet and acne can no longer be dismissed. Compelling evidence shows that hi...

A cne vulgaris is an easily recognizable dermatologic disease. It is also very common. Acne is seen in nearly 100% of individuals at some time during their lives. Small, noninflamed acne lesions may not be more than a slight nuisance but, in individuals with more severe inflammatory nodular acne, pain, social embarrassment, and both physical and psychological scarring can be life altering. Fort...

The lack of effective treatment for acne vulgaris except for long periods of treatment with antibiotics, which increases the risk of developing resistance, is vulnerable. Bio Cool® which is a medical device that has been shown to kill microorganisms in topical treatment especially on the feet. In the present study evaluation was performed to find out whether the product BioCool® alleviates acne...

Acne fulminans is a rare and severe form of acne that may evolve from acne vulgaris, especially in male adolescents, or occur as an adverse effect of oral isotretinoin. Arthritis is a serious clinical manifestation when the musculoskeletal system is compromised by AF and has been reported as a rare adverse effect of isotretinoin. Involvement of the sacroiliac joints occurs in 21% of acne fulmin...

Acne vulgaris is the most common disorder treated by dermatologists. Acne is a disease of pilosebaceous units characterized by the formation of the open and closed comedones, papules, pustules, nodules and cysts. A preliminary trial was conducted in the department of Medicine, National Institute of Unani Medicine, Bangalore, India, to assess the safety and efficacy of a Polyherbal Unani Formula...

Objective. To determine anxiety and depression levels in adolescents with acne vulgaris in relation to clinical severity and gender. Patients and methods. Using a sectional study, the anxiety and depression level was analyzed of 90 adolescents of both sexes, aged 16 to 21 years, who were suffering from acne vulgaris. The study was conducted between February 1st 2008 and January 31st 2009 at the...