The performance of the movable boards ditch opener (MB) and conventional (CD) was compared using disturbed area as a comparison parameter to determine best among two implements. experimental factors were three operating depths (30, 40 50cm) for MB in cultivated uncultivated soils, while CD soil only, because it could not penetrate more than (25cm), angles between (45, 60 750) one angle (650) (t...

Potassium channel openers (KCOs; e.g., P1075, pinacidil) exert their effects on excitable cells by opening ATP-sensitive potassium channels. These channels are heteromultimers composed with a 4:4 stoichiometry of an inwardly rectifying K(+) channel subunit plus a regulatory subunit comprising the receptor sites for hypoglycemic sulfonylureas and KCOs (a sulfonylurea receptor). To elucidate stoi...

The discovery of the mechanism of RNA interference (RNAi) for knockdown of gene expression has spurred a variety of therapeutic applications. An asset of using small interfering RNA (siRNA) as therapeutics is their exquisite sequence-specific mechanism of action. It seems possible that the first RNAi therapy that could reach patients would aim at a debilitating eye disease called age-related ma...

Historically, approaches to exploring complexity have mainly focused on the notion that complex problems must be deconstructed into simpler parts if we are to make sense of them; this is the so-called reductionist approach. When dealing with the complexity of human experience, however, deconstructing the experience without diminishing it is a daunting, perhaps impossible task. Researchers wishi...

Dichlorvos, a synthetic organophosphate toxin, is used as pesticides. These toxins can be used as pesticides in farming and medicine for the devastation and/or elimination of ectoparasites of animals. Reports have shown that Dichlorvos generate seizure effects in various animals. Potassium channel opener is extensively used for medication of cardiovascular and other diseases. Studies have shown...