introduction: allogeneic hematopoietic stem cell transplantation (hsct) has been reported to be a successful curative treatment in aml patients. myeloablative conditioning (mac) is used more frequent as a preparing regimen. this study attempts to compare the outcome of patients who has received mac and reduced- intensity conditioning (ric). methods: totally, 618 patients with aml underwent hsct...

necrotizing fasciitis is a part of a spectrum of necrotizing soft tissue infections that usually follow a surgical intervention or a chronic / acute medical illness. diagnosis is often based on symptoms which classically start within hours after an injury. there are no reports on the use of pet/ct in this condition. sparing reports of its association in patients with malignancy (ca of colon and...

introduction: the majority of leukemia patients are acute leukemia patients, so that about 70.8% lymphoblastic leukemia were acute lymphoblastic leukemia (all) patients and 66.4 % of myeloid leukemia patients were acute myeloid leukemia (aml) in tehran metropolitan. during the last two decades, intensification of therapy by the use of high-dose cytarabine allogeneic stem cell transplantation in...

Background: Environment of Basrah is seriously contaminated with chemical leukomogens as a result of recent military conflicts. Many studies in the past few years have reported an increase in the incidence of leukemia in Basrah. This study was designed to study the risk and pattern of childhood leukemia in Basrah, Iraq, from 2003 to 2007.Materials and Methods: This hospital-based cancer registr...

background: environment of basrah is seriously contaminated with chemical leukomogens as a result of recent military conflicts. many studies in the past few years have reported an increase in the incidence of leukemia in basrah. this study was designed to study the risk and pattern of childhood leukemia in basrah, iraq, from 2003 to 2007.materials and methods: this hospital-based cancer registr...

Resistance to chemotherapy-induced cell death represents a major obstacle in the treatment of acute myeloid leukemia. APRIL (A Proliferation Inducing Ligand) is a member of the tumor necrosis factor superfamily that plays a key role in normal B-cell development, while promoting survival and proliferation of malignant B cells. We investigated APRIL expression and activity in acute myeloid leukem...

................................................................................................................................ 9 INTRODUCTION ..................................................................................................................... 10 REVIEW OF THE LITERATURE ......................................................................................... 11 1. Cancer and ...

BACKGROUND C-type lectin-like molecule-1 is a transmembrane receptor expressed on myeloid cells, acute myeloid leukemia blasts and leukemic stem cells. To validate the potential of this receptor as a therapeutic target in acute myeloid leukemia, we generated a series of monoclonal antibodies against the extracellular domain of C-type lectin-like molecule-1 and used them to extend the expression...

Tiny non-coding RNAs called microRNAs (miRNAs) are crucial for cell survival and differentiation. Numerous cancer varieties, including acute myeloid leukemia, have been linked to abnormal miRNA expression (AML). Objective:

Acute lymphoblastic leukemia, acute myeloid leukemia, gingival enlargement. Abstract Most of the systemic diseases manifest signs and symptoms in oral cavity. Periodontal lesions are common in patients with acute leukemia throughout the course of the disease. Although many cases of gingival enlargement in patients with acute myeloid leukemia have been reported in literature, cases of gingival h...