PURPOSE To retrospectively assess the utility of whole-lesion apparent diffusion coefficient (ADC) metrics in characterizing the Gleason 4 component of Gleason 7 prostate cancer (PCa) at radical prostatectomy. MATERIALS AND METHODS Seventy patients underwent phased-array coil 3T-magnetic resonance imaging (MRI) before prostatectomy. A uropathologist mapped locations and Gleason 4 percentage (...

In this paper, a robust cyclic ADC architecture with βencoder is proposed and circuit scheme using switched-capacitor (SC) circuit is introduced. Different from the conventional binary ADC, the redundancy of proposed cyclic ADC outputs β-expansion code and has an advantage of error correction. This feature makes ADC robust against the offset of comparator capacitor mismatch and finite DC gain o...

BACKGROUND AND PURPOSE Differentiating between primary cerebral lymphoma and glioblastoma multiforme (GBM) based on conventional MR imaging sequences may be impossible. Our hypothesis was that there are significant differences in fractional anisotropy (FA) and apparent diffusion coefficient (ADC) between lymphoma and GBM, which will allow for differentiation between them. MATERIALS AND METHOD...

PURPOSE To investigate the feasibility of targeted biopsy based on an apparent diffusion coefficient (ADC) map in the detection and localization of prostate cancer. MATERIALS AND METHODS This study included 288 consecutive patients with high or increasing serum prostate-specific antigen (PSA) levels who underwent prostatic magnetic resonance imaging (MRI) examination with an ADC map. Four cor...

This paper proposes a column-wise two-step SingleSlope (SS) ADC, which improves the sampling rate while maintaining the architecture of the conventional SS-ADC for high-speed CIS. To remove the problem of missing code in multi-stage structures, occurring on every boundary between steps of the coarse ADC, the range of the fine ADC is doubled to cover the boundary. The sampling rate of the ADC is...

PURPOSE To determine how the ADC value of parotid glands is influenced by the choice of b-values. MATERIALS AND METHODS In eight healthy volunteers, diffusion-weighted echo-planar imaging (DW-EPI) was performed on a 1.5 T system, with b-values (in seconds/mm2) of 0, 50, 100, 150, 200, 250, 300, 500, 750, and 1000. ADC values were calculated by two alternative methods (exponential vs. logarith...

BACKGROUND AND PURPOSE We sought to describe the frequency of normalization of apparent diffusion coefficient (ADC) values that are decreased in hyperacute stroke and to identify characteristics of tissue demonstrating normalization. METHODS Sixty-eight acute ischemic stroke patients underwent MRI examination (including diffusion/perfusion imaging and MR angiography) within 6 hours (mean, 2.8...

OBJECTIVE We elected to analyze the correlation between the pre-treatment apparent diffusion coefficient (ADC) and the clinical, histological, and immunohistochemical status of rectal cancers. MATERIALS AND METHODS Forty-nine rectal cancer patients who received surgical resection without neoadjuvant therapy were selected that underwent primary MRI and diffusion-weighted imaging (DWI). Tumor A...

Purpose: The purpose of this study is to compare the diagnostic accuracy of prostate apparent diffusion coefficient (ADC) versus normalized prostate ADC using the normal peripheral zone as the reference site for the differentiation of prostate cancer and prostatitis in the peripheral zone. Methods: Fifty-two patients, 32 with prostate cancer and 19 with prostatitis, were assessed with single-sh...