INTRODUCTION Many young smokers underestimate their risk for becoming addicted to cigarettes. We explored whether informing light college smokers (i.e., fewer than 5 cigarettes/day) of their genetic predisposition to nicotine dependence influenced their perceived risks and worry about becoming addicted, their ability to quit (i.e., self-efficacy), their desire to quit, and smoking cessation. ...

OBJECTIVES To determine the effect of acetylcholine (ACh), pilocarpine, and atropine on pain evoked responses of pain excited neurons (PEN) and pain inhibited neurons (PIN) in hippocampal CA3 region of morphine addicted rats. MATERIALS AND METHODS Female Wistar rats, weighing between 230-260 g were used in this study. Morphine addicted rats were generated by subcutaneous injection of increasi...

BACKGROUND There is evidence that opium addiction has immunosuppressant effects. Coronary artery disease (CAD) is a condition resulted from atherosclerosis which is dependent on the immune response. PURPOSE To evaluate plasma levels of interleukin-6 and interleukin-1Ra in 30 patients with three-vessel coronary artery disease, ejection fraction of more than 35% and to evaluate their changes af...

background opium addiction is a major issue amongst burn-patients in iran. a few studies have addressed interactions between burn and addiction. objectives the aim of the present study was to compare mortality and morbidity between addicted and non-addicted patients with burn injuries. patients and methods this research was a prospective paired matched-cohort study that was conducted from octob...

3913 Cell Cycle Volume 11 issue 21 Cyclin-dependent kinases (CDKs) drive cell cycle progression and control transcriptional processes. The dysregulation of multiple CDK family members occurs commonly in human cancer; in particular, the cyclin D-CDK4/6-retinoblastoma protein (RB)-iNK4 axis is universally disrupted, facilitating cancer cell proliferation and prompting long-standing interest in ta...

By attempting to quit and seeking help from others, you've already taken a remarkable first step in the direction of change. For those who may be unfamiliar, methadone is a synthetic opioid drug that is commonly used to treat narcotic or opiate addiction (such as heroin). Regardless of whether you started taking methadone to treat a drug addiction, pain, or for recreational purposes, it can be ...

Drug and Alcohol Services, Royal North Shore Hospital, St Leonards, NSW. Stephen M Jurd, MB BS, FRANZCP, FAChAM, Medical Director, Area Drug and Alcohol Services, Northern Sydney Health; and Clinical Senior Lecturer, University of Sydney. Reprints: Dr S M Jurd, Drug and Alcohol Services, Royal North Shore Hospital, Herbert St, St Leonards, NSW 2065. [email protected] The Medical Journal of...

ERIC J. NESTLER and ROBERT C. MALENKA study the molecular basis of drug addiction. Nestler, professor in and chair of the department of psychiatry at the University of Texas Southwestern Medical Center at Dallas, was elected to the Institute of Medicine in 1998. Malenka, professor of psychiatry and behavioral sciences at the Stanford University School of Medicine, joined the faculty there after...

By attempting to quit and seeking help from others, you've already taken a remarkable first step in the direction of change. For those who may be unfamiliar, methadone is a synthetic opioid drug that is commonly used to treat narcotic or opiate addiction (such as heroin). Regardless of whether you started taking methadone to treat a drug addiction, pain, or for recreational purposes, it can be ...