BACKGROUND Opioid replacement treatment (ORT) with methadone is regarded as gold standard in the treatment of opioid addiction. Treatment doses of 60 mg methadone per day and above are associated with better treatment retention and reduction in the use of heroin and cocaine. However, an absolute dose level cannot function as parameter for adequate dosing. This study aims to determine dose adequ...

this paper is based on a research carried out for evaluation of addict rehabilitation centers in iran. the research has been conducted by application of survey method, questionnaire technique and interview with help seekers (addicts) in qarchak varamin rehabilitation and de-addicion center in south- eastern of tehran. this study has been carried out in two stages of pre-treatment and rehabilita...

AIM This study evaluates quasi-compulsory drug treatment (QCT) arrangements for substance-dependent offenders receiving treatment instead of imprisonment in comparison to voluntary treatment within five European countries. METHODS Participants were interviewed with the European Addiction Severity Index, the ASI-crime module, questions on perception of pressure and self-efficacy, and the Readi...

INTRODUCTION Many patients in maintenance treatment programs for opioid dependence are parents to underage children. OBJECTIVE The aim of this study was to explore how parents who are regular patients in maintenance treatment perceive their parenthood. METHODS The study used a qualitative approach. The informants were recruited by staff at a substance abuse clinic in Sweden. Criteria for in...

Dropout and recidivism from addiction treatment has been found to be associated with individuals' readiness for change. Motivation for treatment among participants entering the North American Opiate Medication Initiative (NAOMI) randomized controlled trial, which compared heroin assisted treatment (HAT) to optimized methadone maintenance treatment (MMT), was assessed. Through multivariate regre...

Given that buprenorphine + naloxone is prescribed for opioid-dependent pregnant women, it is important to examine the extent to which it differs from buprenorphine alone, methadone, or methadone-assisted withdrawal on neonatal and maternal outcomes. Summary statistics on maternal and neonatal outcomes were collected from 7 previously published studies examining treatment for opioid-dependent pr...

BACKGROUND Addiction treatment is an effective strategy used to reduce drug-related harm. In the wake of recent developments in novel addiction treatment modalities, we conducted a longitudinal data analysis to examine factors associated with inability to access addiction treatment among a prospective cohort of persons who inject drugs (PWID). METHODS Data were derived from two prospective co...

Substance use is a frequent problem in schizophrenia, and although many substance misusing patients with the disorder also experience considerable cognitive impairments, such individuals have been routinely excluded from clinical trials of cognitive remediation that could support their functional and addiction recoveries. This study conducted a small-scale feasibility trial of Cognitive Enhance...

AND INTRODUCTION One pharmacological treatment for opiate addiction is maintenance on opioid agonists (McKim, 2007). Maintenance drugs alleviate withdrawal symptoms, reduce craving, and block some of the effects of heroin, thereby decreasing the likelihood of relapse and drug-associated criminal behavior (McKim, 2007). Methadone is an orally-administered mu-opioid agonist, which was approved fo...