The purpose of the study was to investigate the influence of VF and the VA on vision related quality of life (VRQoL) in advanced glaucoma. Subjects consist of 50 glaucoma patients with mean deviation (MD) less than -20 dB in at least one eye. Patients' VRQoL was assessed using the 'Sumi questionnaire'. The impact of seven visual measures on VRQoL were compared using principal component regressi...

VISUAL FIELD PRESERVATION IN ADVANCED PRIMARY OPEN-ANGLE GLAUCOMA AFTER FILTRATION SURGERY Traverse C.E., Semino E., Morescalchi F., Corazza M., Gandolfo E., Zingirian M. University Eye Clinic of Genoa (Italy) PURPOSE: To evaluate Visual Field (V.F.) changes in patients with advanced primary open-angle glaucoma undergoing filtration surgery. METHODS: Selection criteria: preoperative IOP z= 21 m...

Introduction . Glaucoma is a socially significant disease. With the advent of new technologies it has become possible to diagnose this disease at an earlier stage. The aim investigation was reveal relationships between biomechanical parameters optic nerve disc (OND) in patients with primary open-angle glaucoma (POAG) against background achieving "target" intraocular pressure (IOP). Material and...

PURPOSE To test the glaucoma-discriminating ability of a new method for detecting local ganglion cell loss using spectral-domain optical coherence tomography (OCT). METHODS This study included 58 glaucomatous and 48 healthy eyes from Japanese subjects. Combined thickness of the ganglion cell layer and inner plexus layer (GCIPL) was measured on a macular cube scan in Cirrus HD-OCT. Average GCI...

Elevated intraocular pressure (IOP) in glaucoma causes loss of retinal ganglion cells (RGCs) and damage to the optic nerve. Although IOP is controlled pharmacologically, no treatment is available to restore retinal and optic nerve function. We evaluated the effects of NGF eye drops in a rat model of glaucoma. We also treated 3 patients with progressive visual field defects despite IOP control. ...

PURPOSE To investigate the usefulness of visual field testing in the diagnosis and subsequent management of glaucoma in a specialist glaucoma clinic at Groote Schuur Hospital, Cape Town, South Africa. METHODS A retrospective case note review of 344 patients who attended the glaucoma clinic between January and June 2010. RESULTS The study population consisted of 201 (58%) females and 143 (42...

BACKGROUND/AIMS To determine the sensitivity and the specificity of the GDx in the detection of (1) advanced glaucoma, (2) early glaucoma, and (3) nerve fibre bundle defects (NFBD). METHODS Group A comprised 20 eyes with reproducible glaucomatous visual field defects confirmed by octopus perimetry, group B consisted of 10 eyes with normal visual fields but either glaucomatous NFBD or deterior...

AbstractGLAUCOMA is a chronic eye disease that can damage optic nerve. According to WHO It is the second leading cause of blindness, and is predicted to affect around 80 million people by 2020. Development of the disease leads to loss of vision, which occurs increasingly over a long period of time. As the symptoms only occur when the disease is quite advanced so that glaucoma is called the sile...

Aims: To compare retrobulbar hemodynamic measured by colour Doppler imaging (CDI) in patients with a different severity of glaucoma and to correlate variables CDI the structural parameters retina optic disc.Material methods: Of 89 eyes studied, 31 had preperimetric, 29 early, 12 moderate 17 advanced glaucoma. Peak systolic velocity (PSV), end-diastolic (EDV), resistance index (RI) ophthalmic ar...

Background/aims: To determine the sensitivity and the specificity of the GDx in the detection of (1) advanced glaucoma, (2) early glaucoma, and (3) nerve fibre bundle defects (NFBD). Methods: Group A comprised 20 eyes with reproducible glaucomatous visual field defects confirmed by octopus perimetry, group B consisted of 10 eyes with normal visual fields but either glaucomatous NFBD or deterior...