Study ObjectiveThe immunohistochemical expression of isoform B the progesterone receptor (PRB) has shown promising results in predicting response atypical endometrial hyperplasia (AEH) and early cancer (EEC) to conservative treatment. We aimed calculate accuracy PRB as a predictive marker treatment outcome AEH or EEC.DesignRetrospective cohort study.SettingUniversity Naples Federico II, Naples,...

We read the article by Minig et al. [1] with great interest. The authors evaluated the efficacy of levonorgestrel-releasing intrauterine device (LNG-IUD) and gonadotropin-releasing hormone (GnRH) for treating patients with atypical endometrial hyperplasia (AEH) or early-stage endometrial cancer, grade I, who wanted to maintain their fertility. The research demonstrated that the combined therapy...

Background Medical management of atypical endometrial hyperplasia (AEH) includes oral or intrauterine progestins. This study aims to evaluate the oncological and reproductive outcomes these patients predictive factors for disease regression, as well compare treatment efficacy different forms Methodology retrospective was conducted at KK Women’s Children’s Hospital, Singapore. Women diagnosed wi...

The study of the "genetic architecture" essential hypertension (EH) is becoming increasingly relevant, in particular, genetic component production peptides, which are used as biomarkers cardiology. Soluble ST2 interleukin-1 receptor family a promising marker myocardial remodeling. basis - SNP rs950880 IL1RL1 gene requires detailed analysis. aim was to prevalence SNR polymorphic variants among m...

BACKGROUND The extent of gut microbial translocation, which plays roles in HIV disease progression and non-AIDS comorbidities, appears to vary with the composition of the gut microbiome, particularly the presence of Lactobacillales, which reduce mucosal injury. While low proportions of Lactobacillales in the distal gut microbiome are a very promising indicator of microbial translocation, measur...

BACKGROUND Metformin, widely used in the treatment of type 2 diabetes mellitus, reduces the risk of cancer and relapse after treatment. Fertility-sparing treatment for endometrial cancer (EC) with progestin is associated with a high chance of disease regression, and the high relapse rate continues to be a problem. We assessed the efficacy of metformin in preventing recurrence after medroxyproge...

In this paper we introduce the SpeakCorrect system which is a Computer Aided Pronunciation Training (CAPT) system for native Arabic students of English. The system is designed with optimized performance for the target users group. It is L1 dependent system and only the frequent pronunciation errors of native Arabic speakers are examined. Several adaptation techniques such as Speaker Adaptive Tr...

infections Widad Al-Nakib, FRCPath, FIDSA; Sahar Essa, BSc, MSc, PhD; Haya Altawalah, BSc, MBBS, FRCPath; Abdullah Owayed; Mousa Khadadah; Nasser Behbehani; Microbiology Department Kuwait University, Faculty of Medicine, Kuwait; Virology Unit, Ministry of Health, Mubarak Hospital, Kuwait; Paediatrics, Kuwait University, Faculty of Medicine, Kuwait; Medicine, Kuwait University, Faculty of Medici...

An analytic study was conducted on coupled partial differential equations. We formally derived new solitary wave solutions of generalized coupled system of Zakharov-Kuznetsov (ZK) and KdV equations by using modified extended tanh method. The traveling wave solutions for each generalized coupled system of ZK and KdV equations are shown in form of periodic, dark, and bright solitary wave solution...

Graz University of Technology, Institute of Environmental Biotechnology, Petersgasse 12, A6 8010 Graz, Austria; Julius Kühn-Institut (JKI), Messeweg 11, D-38104 Braunschweig, 7 Germany, Kawanda Agricultural Research Institute, National Banana Research Program, 8 Uganda; Makerere University, Department of Agricultural Production, College of 9 Agricultural and Environmental Sciences, Uganda and B...