Medicinal plants (e.g. Discaria americana) have been used by populations for centuries. However, popular use is not enough to validate these plants as safe and effective medicinal products. The present study sought to evaluate the acute and subacute toxicity as well as the anxiolytic and antinociceptive effects of D. americana root bark and aerial parts extracts in mice. In acute toxicity studi...

Background & Aim: Essential oil of pennyroyal (Mentha pulegium L.) has many applications in food, perfume and pharmaceutical industries. The aim of this study was to determine the content and chemical constituents of pennyroyal essential oil growing wild in Southern Iran. Experimental: The aerial parts of the plant were collected around Hajiabad, Hormozgan province in 2013. The essent...

The present study aimed the evaluation of allelopathic effect of hydroalcoholic extract from the aerial parts of Mikania scandens (L.) Willd. (Asteraceae); against the germination and radicle growth of Cicer arietinum and Triticum aestivum seeds. The extract at different concentrations was incubated in controlled conditions with the surface sterilized seeds of C. arietinum and T. aestivum and o...

Abstract Five flavonol glycosides, including a new glutaryl-conjugated compound, were isolated from methanolic extract of the endemic Balkan species Astragalus thracicus Griseb. Based on NMR and MS spectra, one compound was identified as kaempferol 3-O-[?-glucopyranosyl-(1?4)-?-rhamnopyranosyl-(1?6)-(2-3-hydroxy-3-methylgutaroyl)-?-galactopyranoside)] (1). The other compounds, all known, maurit...

Abstract Anti-nociceptive activity of aerial parts of Phytolacca americana were investigated, using the hot plate method in mice. Results of the present study showed that the aqueous methanolic extract of aerial parts of P. americana produced a statistically significant increase in pain threshold after 30 min, in comparison with the control, at adose of 190 mg kg-1 (P 0.05). The anti-nociceptiv...